INTRODUCTIONPemphigus vulgaris (PV) refers to a group of autoimmune, blistering diseases that results in lesions affecting predominantly the mucosa and skin. Autoantibodies (anti-Dsg1 and anti-Dsg3) target desmogleins (Dsg1 and Dsg3),…
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INTRODUCTIONPemphigus is a rare autoimmune blistering disease that is associated with significant morbidity and mortality. Rituximab demonstrated superiority over oral steroid monotherapy and steroid-sparing agent mycophenolate in prior clinical trials…
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INTRODUCTIONAndrogenetic alopecia (AGA) results in progressive hair loss due to miniaturization of hair follicles secondary to androgen influence.1 AGA affects both men and women and is a common dermatologic complaint…
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INTRODUCTIONCompounding pharmacies are pharmacies that can prepare unique formulations of topical medications, modify existing formulations of drugs, and create a variety of off-label formulations specific to a patient's needs. These…
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INTRODUCTIONSensitive skin (SS) is a subjective syndrome of cutaneous hyperreactivity, characterized by symptoms of redness, itching, burning, tightness, or stinging in response to innocuous stimuli.1,2 SS is common, with an…
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INTRODUCTIONA recent literature review suggested that the ef fectiveness of sebaceous hyperplasia (SH) treatment was attributed to lesion severity, patient-specific qualities, and cost, rather than a specific treatment modality.1 Ambiguity…
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INTRODUCTIONHidradenitis suppurativa (HS) is a chronic, inflammatory skin condition characterized by abscesses, nodules, fistulae, draining sinus tracts, and scarring.1 Though the pathogenesis of HS is not fully understood, the disease…
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INTRODUCTIONChronic itch is common among older adults, however, without overt serologic or histologic abnormalities, many geriatric patients have no discernible cause of their pruritus. In these cases, it is postulated…
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To The Editor, Few surveyed practitioners provide medical intervention for vitiligo in the Netherlands.1 In a recent United Kingdom qualitative patient survey, patients reported that their physicians had low awareness…
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INTRODUCTIONMelasma is an acquired, pigmentary disorder characterized by the appearance of light brown to dark macules on sun-exposed areas of the body, most commonly occurring on the face. It can…
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INTRODUCTIONChronic venous insufficiency (CVI) comprises structural and functional pathology of the venous system. CVIs' pathophysiology most commonly results from lower extremity valvular reflux and/or venous obstruction, which induces sustained elevated…
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INTRODUCTIONTopical onychomycosis therapies require extended treatment durations, and incomplete treatment can contribute to high relapse rates.1 Excellent treatment adherence is vital to optimize outcomes2 and requires that an adequate quantity…
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