Found 12 articles for: "sarecycline"
October 2021 | Volume 20 | Issue 10 | Original Article | 1031 | Copyright © October 2021
2021 is the 50th anniversary of the FDA approval of minocycline (MCN). While many other antibiotics have become obsolete during this time, MCN continues to be quite useful. In dermatology, MCN is used...
June 2021 | Volume 20 | Issue 6 | Original Article | 648 | Copyright © June 2021
Background: The Food and Drug Administration (FDA) recommends grading Acne vulgaris via an Investigator’s Global Assessment (IGA) scale and assessing treatment as either success...
June 2021 | Volume 20 | Issue 6 | Original Article | 634 | Copyright © June 2021
Background: Acne vulgaris is a common skin disease that affects the face, chest, and back. While truncal acne is present in at least 50% of patients, clinical studies have focused pre...
Oral Sarecycline for Treatment of Papulopustular Rosacea: Results of a Pilot Study of Effectiveness and Safety
April 2021 | Volume 20 | Issue 4 | Original Article | 426 | Copyright © April 2021
Background: Cutaneous rosacea is a common inflammatory skin disorder that often presents with facial papulopustular lesions that are frequently bothersome to patients. Studies have sh...
January 2021 | Volume 20 | Issue 1 | Case Reports | 98 | Copyright © January 2021
Broad spectrum tetracyclines are a well-known, widely used, and often successful treatment for use in inflammatory skin pathologies such as acne and rosacea. However, the steady rise of antibiotic res...
November 2020 | Volume 19 | Issue 11 | Supplement Individual Articles | s6 | Copyright © November 2020
Oral tetracyclines are the most widely prescribed systemic antibiotic for acne. Synthesis of efficacy and safety of traditional and novel oral tetracyclines is highly informative to clinical practice....
November 2020 | Volume 19 | Issue 11 | Supplement Individual Articles | s5 | Copyright © November 2020
Dermatologists consistently rank as the most frequent prescribers of systemic antibiotics, and one of the most common diagnoses for which we recommend these agents is acne vulgaris. Up to three quarte...
June 2020 | Volume 19 | Issue 6 | Original Article | 592 | Copyright © June 2020
Background: Acne vulgaris is the most common dermatological disorder. Pediatric acne may be a manifestation of the underlying pathology and can occur in the first weeks, months, or ye...
June 2020 | Volume 19 | Issue 6 | Original Article | 639 | Copyright © June 2020
Background: The Food and Drug Administration (FDA) has approved several new dermatologic drugs in the last decade. The public response to their approval has not yet been evaluated.
June 2019 | Volume 18 | Issue 6 | Original Article | 506 | Copyright © June 2019
Rosacea is common inflammatory facial dermatosis. Rosacea has variable manifestations including facial flushing, central facial erythema, telangiectasias, and papulopustular lesions. Treatment of rosa...
Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials
September 2018 | Volume 17 | Issue 9 | Original Article | 987 | Copyright © September 2018
Background: Side effects may limit the use of current tetracycline-class antibiotics for acne. Objective: Evaluate the efficacy and safety of once-daily sarecycline, a novel, narrow-spectrum tetracycl...
Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study
March 2018 | Volume 17 | Issue 3 | Case Reports | 333 | Copyright © March 2018
BACKGROUND: There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically desig...