Found 471 articles for: "retinoids"
Nontraditional Management of Basal Cell Carcinoma
May 2013 | Volume 12 | Issue 5 | Original Article | 525 | Copyright © May 2013
This review discusses nontraditional modalities available for the treatment of basal cell carcinoma along with the existing evidence to support their respective uses in varying clinical situations. By...
Read MorePeriungual Pyogenic Granuloma Following Imatinib Therapy in a Patient With Chronic Myelogenous Leukemia
May 2013 | Volume 12 | Issue 5 | Editorials | 512 | Copyright © May 2013
The Therapeutic Role of Isotretinoin in the Management of Behçet's Disease: A Single-Blinded, Controlled Therapeutic Study
April 2013 | Volume 12 | Issue 4 | Original Article | 68 | Copyright © April 2013
OBJECTIVES: To evaluate the long-term remission efficacy and safety of isotretinoin in the treatment of Behcet's disease (BD).
PATIENTS and METHODS: This single-blind, controlled therapeutic stu...
Read MoreThe Therapeutic Effects of a Topical Tretinoin and Corticosteroid Combination for Vitiligo: A Placebo-Controlled, Paired-Comparison, Left-Right Study
April 2013 | Volume 12 | Issue 4 | Original Article | 63 | Copyright © April 2013
BACKGROUND: Topical all-trans-retinoic acid (tretinoin) prevents skin atrophy induced by long-term use of topical corticosteroids, without abrogating their anti-inflammatory effects.
OBJECTIVE: ...
Read MoreVitamin A and Its Derivatives in Experimental Photocarcinogenesis: Preventive Effects and Relevance to Humans
April 2013 | Volume 12 | Issue 4 | Original Article | 458 | Copyright © April 2013
The 1925 classical observation that vitamin A deficiency leads to squamous metaplasia and epithelial keratinization, coupled with the later finding that excess vitamin A inhibits keratinization of chi...
Read MoreThe Effects of Filtrate of the Secretion of the Cryptomphalus aspersa on Photoaged Skin
April 2013 | Volume 12 | Issue 4 | Original Article | 453 | Copyright © April 2013
BACKGROUND: Growth factors (GFs) are chemical messengers that regulate specific cellular activities such as cell proliferation and formation of the extracellular matrix. GFs may be derived from a vari...
Read MoreThe Efficacy and Tolerability of Tazarotene Foam, 0.1%, in the Treatment of Acne Vulgaris in 2 Multicenter, Randomized, Vehicle-Controlled, Double-Blind Studies
April 2013 | Volume 12 | Issue 4 | Original Article | 438 | Copyright © April 2013
BACKGROUND: Tazarotene 0.1% gel and cream are effective topical treatments for acne. Tazarotene foam, 0.1% was developed to provide an alternative, safe, and effective formulation.
OBJECTIVE: To...
Read MoreRetinoids and Azelaic Acid to Treat Acne and Hyperpigmentation in Skin of Color
April 2013 | Volume 12 | Issue 4 | Original Article | 434 | Copyright © April 2013
In this review, we examine published data reporting the efficacy of pharmaceutical agents to treat associated postinflammatory hyperpigmentation commonly seen in skin of color. Read More
Comparative Study of Hydroquinone-Free and Hydroquinone-Based Hyperpigmentation Regimens in Treating Facial Hyperpigmentation and Photoaging
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 32 | Copyright © March 2013
BACKGROUND: Photoaged skin, characterized by mottled, irregular areas of pigmentation, is a common skin condition that is often difficult to treat. The areas of hypermelanosis are an aesthetic concern...
Read MoreSafety and Efficacy of a Novel Multimodality Hydroquinone-Free Skin Brightener Over Six Months
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 27 | Copyright © March 2013
BACKGROUND: Abnormal accumulation of melanin is a common aesthetic skin concern. For years, the gold standard for the treatment of hyperpigmentary disorders has been 4% hydroquinone (HQ). Due to regul...
Read MoreClinical Efficacy and Safety of a Multimodality Skin Brightener Composition Compared With 4% Hydroquinone
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 21 | Copyright © March 2013
There are numerous common skin disorders involving hyperpigmentation, including solar lentigines, postinflammatory hyperpigmentation, melasma, freckles, and dyschromia from photoaging. While these con...
Read MoreA Status Report on Topical Tazarotene in the Management of Acne Vulgaris
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 53 | Copyright © March 2013
Tazarotene is a synthetic retinoid that, depending on the concentration and vehicle, is approved by the US Food and Drug Administration for the topical treatment of acne vulgaris (AV) and plaque psori...
Read MoreThe Only Topical Retinoid Without a Generic Alternative: Tazarotene
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 52 | Copyright © March 2013
Sustained Clinical Resolution of Acquired Epidermodysplasia Verruciformis in an Immunocompromised Patient After Discontinuation of Oral Acitretin With Topical Imiquimod
March 2013 | Volume 12 | Issue 3 | Case Reports | 348 | Copyright © March 2013
Increased cases of acquired epidermodysplasia verruciformis (EDV) have been reported in patients with human immunodeficiency virus (HIV). With regard to management, there are no randomized controlled ...
Read MoreThe Efficacy of Ustekinumab in Psoriasis
March 2013 | Volume 12 | Issue 3 | Original Article | 317 | Copyright © March 2013
Psoriasis is an immune-mediated cutaneous disease affecting 2% of the worldwide population. While topical therapy, phototherapy, oral systemic therapy, and biologic agents have been used, the treatmen...
Read MoreEfficacy of Topical 4% Quassia amara Gel in Facial Seborrheic Dermatitis:A Randomized, Double-Blind, Comparative Study
March 2013 | Volume 12 | Issue 3 | Original Article | 312 | Copyright © March 2013
BACKGROUND: Seborrheic dermatitis (SD) is a chronic mild skin disorder with high prevalence. Various treatment options are available, including topical antifungals and anti-inflammatories. Antifungal ...
Read MoreA Multicenter, Randomized, Double-Blind Study of the Efficacy and Safety of Calcipotriene Foam, 0.005%, vs Vehicle Foam in the Treatment of Plaque-type Psoriasis of the Scalp
March 2013 | Volume 12 | Issue 3 | Original Article | 300 | Copyright © March 2013
BACKGROUND: Calcipotriene ointment and cream are effective treatments for psoriasis, but many patients with scalp psoriasis prefer lighter, less messy vehicles.
OBJECTIVES: To evaluate the effic...
Read MoreEfficacy and Safety of Tretinoin 0.025%/Clindamycin Phosphate 1.2% Gel in Combination With Benzoyl Peroxide 6% Cleansing Cloths for the Treatment of Facial Acne Vulgaris
March 2013 | Volume 12 | Issue 3 | Original Article | 277 | Copyright © March 2013
Combination therapy using medications with complementary mechanisms of action is the standard of care in treating acne. We report results of a clinical trial evaluating the use of a fixed-dose tretino...
Read MoreComparison of a Skin-Lightening Cream Targeting Melanogenesis on Multiple Levels to Triple Combination Cream for Melasma
March 2013 | Volume 12 | Issue 3 | Original Article | 270 | Copyright © March 2013
The safety and efficacy of a novel skin-lightening cream (SLC) with 4% hydroquinone (HQ), which additionally contains 4 skin-brightening actives, was compared with a triple combination cream (TCC) wit...
Read MoreComparison of Clindamycin 1% and Benzoyl Peroxide 5% Gel to a Novel Composition Containing Salicylic Acid, Capryloyl Salicylic Acid, HEPES, Glycolic Acid, Citric Acid, and Dioic Acid in the Treatment of Acne Vulgaris
March 2013 | Volume 12 | Issue 3 | Original Article | 266 | Copyright © March 2013
This study evaluated the tolerance and efficacy of 2 facial skin products in subjects with acne using the following acne treatments: 1) treatment A, a combination of salicylic acid, capryloyl salicyli...
Read More