Found 471 articles for: "retinoids"
News, Views, and Reviews. Myocosis Fungoides-An Update on a Non-Mycotic Disease
July 2013 | Volume 12 | Issue 7 | Features | 825 | Copyright © July 2013
Mycosis fungoides was first described in 1806 by the French physician Jean Louis Alibert in a patient whose skin lesions developed into mushroom-like tumors. Though it is not an infectious disease,...
Read MorePhotopneumatic Therapy for the Treatment of Keratosis Pilaris
July 2013 | Volume 12 | Issue 7 | Original Article | 804 | Copyright © July 2013
BACKGROUND: Current treatment options for keratosis pilaris (KP) are limited and are often found to be unsatisfactory to patients.
OBJECTIVE: Pilot study to determine if photopneumatic therapy (P...
Read MoreAcitretin Prescribing Patterns in Women of Childbearing Potential
July 2013 | Volume 12 | Issue 7 | Original Article | 799 | Copyright © July 2013
BACKGROUND: Acitretin is indicated for severe psoriasis, but it is also a potent teratogen whose use should be avoided in women of childbearing potential. Topical medications, phototherapy, cyclospori...
Read MoreThe Efficacy, Safety, and Tolerability of Adapalene Versus Benzoyl Peroxide in the Treatment of Mild Acne Vulgaris: A Randomized Trial
July 2013 | Volume 12 | Issue 7 | Original Article | 790 | Copyright © July 2013
Topical treatments, such as adapalene and benzoyl peroxide (BPO), are popular in mild-to-moderate acne vulgaris. This study aimed to compare the efficacy, safety and tolerability of adapalene and BPO ...
Read MoreOpen-Label Evaluation of a Novel Skin Brightening System Containing 0.01% Decapeptide-12 in Combination With 20% Buffered Glycolic Acid for the Treatment of Mild to Moderate Facial Melasma
June 2013 | Volume 12 | Issue 6 | Original Article | 106 | Copyright © June 2013
Melasma is a cutaneous disorder that primarily affects females of Hispanic and Asian descent. Previous studies have shown that use of a brightening system comprised of 0.01% decapeptide-12 cream, an ...
Read MorePipeline Previews
June 2013 | Volume 12 | Issue 6 | Features | 718 | Copyright © June 2013
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from th...
Read MoreGranuloma Annulare Masquerading as Erythema Multiforme
June 2013 | Volume 12 | Issue 6 | Case Reports | 694 | Copyright © June 2013
Erythema multiforme (EM) is a serious cutaneous and/ or mucocutaneous disorder that typically develops within 10-14 days of exposure to an offending medication or infection and resolves within 4 week...
Read MoreA Randomized, Phase 2, Dose-Ranging Study in the Treatment of Moderate to Severe Inflammatory Facial Acne Vulgaris With Doxycycline Calcium
June 2013 | Volume 12 | Issue 6 | Original Article | 658 | Copyright © June 2013
BACKGROUND: Doxycycline calcium (WC2055) is a drug substance with a possible role in the treatment of acne. The objective of this study was to evaluate the safety and efficacy of three doses of doxyc...
Read More40 Years of Topical Tretinoin Use in Review
June 2013 | Volume 12 | Issue 6 | Original Article | 638 | Copyright © June 2013
Topical tretinoin has been approved for use in dermatology for 40 years and is currently approved for the treatm...
Read MoreA Single-Center, Randomized Double-Blind, Parallel-Group Study to Examine the Safety and Efficacy of 3mg Drospirenone/0.02mg Ethinyl Estradiol Compared With Placebo in the Treatment of Moderate Truncal Acne Vulgaris
June 2013 | Volume 12 | Issue 6 | Original Article | 633 | Copyright © June 2013
BACKGROUND: Acne is a common disease of the face, chest and back, initially triggered by androgens. 3mg Drospirenone (DRSP)/0.02mg ethinyl estradiol (EE), an oral contraceptive and antiandrogen, has ...
Read MoreClinical Relevance of Skin Barrier Changes Associated With the Use of Oral Isotretinoin: The Importance of Barrier Repair Therapy in Patient Management
June 2013 | Volume 12 | Issue 6 | Original Article | 626 | Copyright © June 2013
Oral isotretinoin is a non-aromatic oral retinoid that is highly effective for the treatment of severe inflammatory acne vulgaris that is refractory and/or prone to scarring, and has also been used s...
Read MorePreadolescent Moderate Acne Vulgaris: A Randomized Trial of the Efficacy and Safety of Topical Adapalene-Benzoyl Peroxides
June 2013 | Volume 12 | Issue 6 | Original Article | 611 | Copyright © June 2013
OBJECTIVE: Evaluate the efficacy and safety of adapalene 0.1%-benzoyl peroxide 2.5% gel (adapalene-BPO) in patients 9-11 years old with acne vulgaris.
METHODS: Enrolled subjects were male or f...
Read MoreThe Role of Benzoyl Peroxide in the New Treatment Paradigm for Acne
June 2013 | Volume 12 | Issue 6 | Supplement Individual Articles | 73 | Copyright © June 2013
Bacterial resistance became a true clinical concern for dermatologists in the 1980s, when the first reports emerged of the resistance of Propionibacterium acnes to oral antibiotics. Subsequen...
Read MoreMessages From Molecules: Deciphering the Code
June 2013 | Volume 12 | Issue 6 | Supplement Individual Articles | 70 | Copyright © June 2013
Acne therapy should be based on pathogenesis. Current mainstays of therapy include topical retinoids, antibiotics, and benzoyl peroxide. Newer research has shown that inflammation may precede comedo f...
Read MoreWhat's New in Acne and Inflammation?
June 2013 | Volume 12 | Issue 6 | Supplement Individual Articles | 67 | Copyright © June 2013
Acne is a disease that leaves physiological as well as physical scars. As we attempt to understand this complicated disease, new research challenges our traditional understanding that the microcomedon...
Read MoreAcne: Evolving Concepts of Pathogenesis Need to Guide Therapeutic Developments
June 2013 | Volume 12 | Issue 6 | Supplement Individual Articles | 66 | Copyright © June 2013
Sign and Pseudo-Sign of Leser-Trélat: Case Reports and a Review of the Literature
May 2013 | Volume 12 | Issue 5 | Original Article | 79 | Copyright © May 2013
BACKGROUND: Leser-Trélat is distinguished by a rare paraneoplastic sign that is characterized by the sudden eruption of multiple seborrheic keratoses (SKs), associated with underlying internal ma...
Read MoreNews, Views, & Reviews
Hair Loss in the Dermatology Office: An Update on Alopecia AreataMay 2013 | Volume 12 | Issue 5 | Features | 588 | Copyright © May 2013
The Clinical Effects of Zinc as a Topical or Oral Agent on the Clinical Response and Pathophysiologic Mechanisms of Acne: A Systematic Review of the Literature
May 2013 | Volume 12 | Issue 5 | Original Article | 542 | Copyright © May 2013
This article reviews the published literature about the efficacy of oral and topical zinc as treatments for acne vulgaris. The medical literature was systematically reviewed to identify relevant artic...
Read MoreTreatment of Facial Photodamage Using a Novel Retinol Formulation
May 2013 | Volume 12 | Issue 5 | Original Article | 533 | Copyright © May 2013
BACKGROUND: Photoaged skin is characterized by a variety of clinical, histologic, and biochemical features.
OBJECTIVE: To determine the efficacy of a new topical formulation of 1% retinol and t...
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