Found 929 articles for: "acne"
Multi-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation
April 2018 | Volume 17 | Issue 4 | Original Article | 426 | Copyright © April 2018
Background/Objectives: Anti-aging strategies utilizing stem cells are in the forefront. Alpha and beta defensins are natural immune peptides that have been shown to activate an LGR6-positive stem cell...
Read MoreTopical Agents for Scar Management: Are They Effective?
April 2018 | Volume 17 | Issue 4 | Original Article | 421 | Copyright © April 2018
Scar formation is the body’s natural healing response to reestablish dermal integrity following an injury. Excessive scarring, however, can cause significant cosmetic, functional, and psychological ...
Read MoreFrontal Fibrosing Alopecia and Concomitant Lichen Planus Pigmentosus: A Case Series of Seven African American Women
April 2018 | Volume 17 | Issue 4 | Original Article | 397 | Copyright © April 2018
The association of frontal fibrosing alopecia (FFA) and lichen planus pigmentosus (LPPigm) is rare. Prior reports suggest that FFA and LPPigm are on the same spectrum of disease, and a diagnosis of LP...
Read MoreAn Acne Survey from the World’s Largest Annual Gathering of Twins
April 2018 | Volume 17 | Issue 4 | Original Article | 380 | Copyright © April 2018
IMPORTANCE: Surveying identical twins allows us to qualitatively separate genetic and environmental factors that may contribute to acne severity. OBJECTIVE: To study a cohort of identical and fratern...
Read MoreEfficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study
March 2018 | Volume 17 | Issue 3 | Case Reports | 333 | Copyright © March 2018
BACKGROUND: There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically desig...
Read MoreIntramuscular Steroids in the Treatment of Dermatologic Disease: A Systematic Review
March 2018 | Volume 17 | Issue 3 | Original Article | 323 | Copyright © March 2018
IMPORTANCE: Intramuscular (IM) steroids can be used to treat a wide variety of dermatologic diseases. Although seemingly effective and safe, this form of corticosteroid therapy may be underused amongs...
Read MorePhase 2 Randomized, Dose-Ranging Study of Oxymetazoline Cream for Treatment of Persistent Facial Erythema Associated With Rosacea
March 2018 | Volume 17 | Issue 3 | Original Article | 308 | Copyright © March 2018
Background: Rosacea is a chronic dermatologic condition with limited treatment options. Objective: This phase 2 study evaluated the optimal oxymetazoline dosing regimen in patients with moderate to s...
Read MoreAddressing Male Facial Skin Concerns: Clinical Efficacy of a Topical Skincare Treatment Product for Men
March 2018 | Volume 17 | Issue 3 | Original Article | 301 | Copyright © March 2018
The growing male skincare market reflects the increased interest of men in addressing facial aging concerns and maintaining a healthy youthful appearance. Because of differences in skin structure and ...
Read MorePivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the Second REVEAL Trial
March 2018 | Volume 17 | Issue 3 | Original Article | 290 | Copyright © March 2018
Rosacea is a chronic dermatologic condition with limited treatment options, particularly for persistent erythema. This pivotal phase 3 study evaluated oxymetazoline, an a1A-adrenoceptor agonist, for t...
Read MoreEfficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel Plus Oral Doxycycline in Subjects With Severe Inflammatory Acne Who Are Candidates for Oral Isotretinoin
March 2018 | Volume 17 | Issue 3 | Original Article | 264 | Copyright © March 2018
INTRODUCTION: Acne treatment guidelines suggest a combination approach with topical therapy including a topical retinoid, benzoyl peroxide and an oral antibiotic, or oral isotretinoin (OI), as first-l...
Read MoreEfficacy, Safety, and Tolerability of Topical Dapsone Gel, 7.5% for Treatment of Acne Vulgaris by Fitzpatrick Skin Phototype
February 2018 | Volume 17 | Issue 2 | Original Article | 160 | Copyright © February 2018
BACKGROUND: Acne vulgaris (acne) is prevalent in individuals with skin of color, often with more frequent sequelae than in patients with lighter skin color. It is important to determine if there are a...
Read MoreCross-Sectional Survey of the Burden of Illness of Rosacea by Erythema Severity
February 2018 | Volume 17 | Issue 2 | Original Article | 150 | Copyright © February 2018
Rosacea is a chronic skin condition characterized by persistent central facial erythema. To explore the burden of illness of rosacea in US adults, a cross-sectional web-based survey was conducted. Par...
Read MoreEruptive Sebaceous Hyperplasia: A Rare Consequence of Systemic Corticosteroids
January 2018 | Volume 17 | Issue 1 | Case Reports | 118 | Copyright © January 2018
BACKGROUND: Eruptive sebaceous hyperplasia is a rare and poorly understood consequence of immunosuppression, most commonly with cyclosporine, following organ transplantation. To date, there have been ...
Read MorePivotal Trial of the Efficacy and Safety of Oxymetazoline Cream 1.0% for the Treatment of Persistent Facial Erythema Associated With Rosacea: Findings from the First REVEAL Trial
January 2018 | Volume 17 | Issue 1 | Original Article | 97 | Copyright © January 2018
An unmet need exists for a safe, tolerable, effective treatment for moderate to severe persistent facial erythema in patients with rosacea. This pivotal phase 3, multicenter, double-blind study evalua...
Read MoreInjectable Non-Animal Stabilized Hyaluronic Acid as a Skin Quality Booster: An Expert Panel Consensus
January 2018 | Volume 17 | Issue 1 | Original Article | 83 | Copyright © January 2018
Hyaluronic acid (HA) is used extensively in aesthetic medicine thanks to its documented role in skin rejuvenation. The specific applications of HA-based products are not always fully acknowledged due ...
Read MoreTreatment of Décolletage Photoaging With Fractional Microneedling Radiofrequency
January 2018 | Volume 17 | Issue 1 | Original Article | 74 | Copyright © January 2018
OBJECTIVES: The objective of this study was to examine the efficacy and safety of a novel fractional microneedling radiofrequency device to improve the appearance of rhytides and skin laxity of the dÃ...
Read MorePityriasis Folliculorum: Response to Topical Ivermectin
December 2017 | Volume 16 | Issue 12 | Case Reports | 1290 | Copyright © December 2017
Pityriasis folliculorum has been described as a dry type of rosacea with extensive proliferation of Demodex folliculorum in pilosebaceous follicles of the skin. This skin condition is frequently di...
Read MorePatient Awareness of Local Drug Price Variation and the Factors That Influence Pharmacy Choice: A Cross-sectional Survey Study
December 2017 | Volume 16 | Issue 12 | Original Article | 1274 | Copyright © December 2017
Background: High out-of-pocket drug expenditures are increasingly common in dermatology. Patients may not be aware that prices vary among pharmacies and consequently may not shop for the lowest cos...
Read MoreThe Latest Drugs and Small Molecule Inhibitors for Skin and Hair
December 2017 | Volume 16 | Issue 12 | Original Article | 1224 | Copyright © December 2017
Biologic drugs, a novel class of agents engineered to target specifc mediators of infammation, and small-molecule inhibitors that pen-etrate the cell membrane to interact with targets inside a cell...
Read MoreA New Look at Pathogenesis of Hair Loss
November 2017 | Volume 16 | Issue 11 | Supplement Individual Articles | 133 | Copyright © November 2017
While there are a number of products that can help healthy hair look healthier, shampoos or vitamins alone can’t truly regrow thinning hair. As dermatology providers, we realize this not only...
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