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Self-Reported Long-Term Side Effects of Isotretinoin: A Case Series

By February 7, 2025No Comments

From the Vault

Isotretinoin remains the gold standard for treating severe nodulocystic acne, yet concerns about its potential psychiatric effects continue to spark debate. While high-quality studies have found no direct link between isotretinoin and psychiatric disorders, online communities tell a different story—patients sharing experiences of long-term side effects on social media have gained attention, raising questions dermatologists can’t ignore.

In this article from the vault, it explores self-reported long-term effects of isotretinoin, including psychiatric, gastrointestinal, and neurological symptoms. While causality remains uncertain, this analysis highlights the need for continued research and awareness among dermatologists as social media conversations shape patient perceptions.