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The Potential Risk of Povidone-Iodine in Sperm Quality: A Case Report

By February 24, 2025No Comments
Journal of Drugs in Dermatology JDD Article About The Potential Risk of Povidone-Iodine in Sperm Quality: A Case Report

Featured Case Report

Could your patient’s go-to antiseptic be sabotaging sperm quality? PVP-I (povidone-iodine) is a trusted antimicrobial, but a recent case raises concerns about its impact on male fertility. A 45-year-old patient using PVP-I liniment for a fungal nail infection saw a dramatic drop in sperm quality, which improved after stopping treatment.

While PVP-I’s known side effects include allergic reactions and thyroid dysfunction, its effect on sperm has never been reported—until now. Could iodine absorption and oxidative stress be factors? Read the full case report to learn more.