Found 21 articles for: "efficacy"
Efficacy, Safety, and Real-World Aspects of Janus Kinase Inhibitors to Treat Patients With Alopecia Areata
March 2026 | Volume 25 | Issue 3 | Original Article | 204 | Copyright © March 2026
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss on the scalp and body, leading to a reduced quality of life and psychosocial burden for patients. The only US ...
Read MoreEfficacy and Safety of Clascoterone Cream 1% for Acne Are Independent of Age and Sex
February 2026 | Volume 25 | Issue 2 | Original Article | 119 | Copyright © February 2026
Acne vulgaris is an inflammatory skin condition affecting adolescents and adults of both sexes. Clascoterone cream 1% is indicated for the topical treatment of acne vulgaris in patients ≥12 ye...
Read MoreReal-World Evidence of Brodalumab Effectiveness for the Treatment of Psoriasis
February 2026 | Volume 25 | Issue 2 | Original Article | 126 | Copyright © February 2026
Brodalumab is a recombinant, fully human monoclonal antibody antagonist of the human interleukin-17 (IL-17) receptor A. It is indicated for the treatment of moderate-to-severe plaque psoriasis in...
Read MoreTopical Efinaconazole 10% for Onychomycosis: Pooled Phase 3 Analysis in White, Black, and Asian Participants
January 2026 | Volume 25 | Issue 1 | Original Article | 67 | Copyright © January 2026
Background: Topical efinaconazole 10% solution has demonstrated efficacy and safety in two phase 3 trials of onychomycosis. As clinical data for onychomycosis treatments are limi...
Read MoreClindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% Gel for Moderate-to-Severe Acne: A Pooled Analysis by Age
December 2025 | Volume 24 | Issue 12 | Original Article | 1186 | Copyright © December 2025
Background: Acne pathophysiology and presentation may differ between pediatric/adolescent/young adult (9-24 years) and adult (≥25 years) patients. Fixed-dose clindamycin phosp...
Read MorePerceptions and Recommendations for Sunscreen: A Cross-Sectional Survey of United States Dermatology Healthcare Providers
November 2025 | Volume 24 | Issue 11 | Original Article | 1113 | Copyright © November 2025
Read MoreCaffeine Supplementation and Hair: A Systematic Review
November 2025 | Volume 24 | Issue 11 | Original Article | 1070 | Copyright © November 2025
Background: While caffeine has been proposed to stimulate hair growth, its safety and efficacy remain unclear. This systematic review evaluates the effects of caffeine interventi...
Read MoreClinical Profile of Halobetasol Propionate 0.01%/ Tazarotene 0.045% Lotion in Patients With Hyperkeratotic Plaque Psoriasis
June 2025 | Volume 24 | Issue 6 | Original Article | 590 | Copyright © June 2025
Background: Hyperkeratotic psoriatic plaques, characterized by considerable elevation and scaling, present treatment challenges with topical therapy. This post hoc analysis of tw...
Read MoreA Single-Center Pilot Study to Evaluate the Efficacy, Safety, and Tolerability of Sarecycline for Treating Periorificial Dermatitis
June 2025 | Volume 24 | Issue 6 | Original Article | 617 | Copyright © June 2025
Background: Periorificial dermatitis (POD) is a facial skin rash often found in the oral commissures and nasolabial folds, and around the eyes. Treatment options include topical ...
Read MoreNovel 2% Salicylic Acid Cleanser With Polymeric Cleansing Technology Treats Acne Without Compromising Skin Barrier
June 2025 | Volume 24 | Issue 6 | Original Article | 570 | Copyright © June 2025
Background: A novel acne cleanser containing 2% Salicylic acid (SA), Polymeric Cleansing Technology (PCT), and a microgel complex, was evaluated for its efficacy in treating mild...
Read MoreNeed for Speed: Topical Roflumilast for Rapid Control of Seborrheic Dermatitis Flares
June 2025 | Volume 24 | Issue 6 | Case Reports | 634 | Copyright © June 2025
Seborrheic dermatitis is a common chronic inflammatory skin condition historically treated with topical antifungals and anti-inflammatory agents. While topical corticosteroids are frequently used...
Read MoreClindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% for Acne: Results From A 6-Month Open-Label Study
May 2025 | Volume 24 | Issue 5 | Original Article | 516 | Copyright © May 2025
Background: Treatment of acne may require many months of treatment before maximal benefits are observed, and acne sequelae (eg, scarring, dyspigmentation) can persist long a...
Read MoreGuselkumab Efficacy by Psoriasis Disease Severity and Treatment History: VOYAGE 1 and 2 Post Hoc Analyses
February 2025 | Volume 24 | Issue 2 | Original Article | 196 | Copyright © February 2025
Background: The pivotal Phase 3 VOYAGE 1 and VOYAGE 2 studies established the robust efficacy and safety of guselkumab for up to 5 years in patients with moderate-to-severe psori...
Read MoreLong-Term Efficacy and Tolerability of a Daily Serum for Rejuvenation and Prejuvenation of Facial Skin
September 2023 | Volume 22 | Issue 9 | Original Article | 917 | Copyright © September 2023
Onjectives: To evaluate the long-term efficacy and tolerance of an anti-aging daily serum (AADS) when used twice-daily over 12 weeks by women with moderate skin fatigue and overa...
Read MoreAssessing the Efficacy of Imiquimod Use in Patients With Persistent Locally Advanced Melanoma In Situ
May 2023 | Volume 22 | Issue 5 | Original Article | 457 | Copyright © May 2023
Background: The standard of care when treating melanoma in situ (MMIS) is an excision with at least 5 mm surgical margins.1 Some studies have suggested up to 9 mm margins to maxi...
Read MoreA Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia
April 2023 | Volume 22 | Issue 4 | Original Article | 333 | Copyright © April 2023
Background: Dyschromia can be caused by abnormalities in the increased production and/or reduced clearance of pigmentation in the skin. Causes of hyperpigmentation include excessive s...
Read MoreManaging Monkeypox Virus: Characterizing Common Cutaneous Manifestations and Antiviral Efficacy
March 2023 | Volume 22 | Issue 3 | Original Article | 282 | Copyright © March 2023
Background: The Monkeypox virus (MPX) has been detected in multiple non-endemic countries since May 2022. The cutaneous manifestations of MPX can have multiple distinct presentat...
Read MoreThe Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study
February 2023 | Volume 22 | Issue 2 | Original Article | 139 | Copyright © February 2023
Background: Patients with atopic dermatitis (AD) need safe and effective topical treatments.
Objective: To assess safety and efficacy of roflumilast cream in pa...
Read MoreEfficacy and Safety of Calcipotriene/Betamethasone Dipropionate Foam in the Treatment of Psoriasis in Skin of Color
February 2023 | Volume 22 | Issue 2 | Original Article | 165 | Copyright © February 2023
Background: There is a paucity of data on usage of topical medications in patients with darker phototypes. This single-center, randomized, double-blinded, vehicle-controlled clinical ...
Read MoreEfficacy and Safety of 1% Clascoterone Cream in Patients Aged > 12 Years With Acne Vulgaris
February 2023 | Volume 22 | Issue 2 | Original Article | 174 | Copyright © February 2023
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