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View the Latest Discoveries in Skin Cancer Research

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Dermatology Resource Centers

JDD Resource Centers

Stay up-to-date on new clinical findings in Skin Cancer  View the latest articles, case reports, supplements, Podcast episodes and more!

Skin Cancer Resource Center

The Latest Clinical Findings in Skin Cancer

Discover the latest research in Skin Cancer: introducing the JDD Skin Cancer Resource Center.

Review clinical findings, articles, case reports, supplements, podcast episodes and more.

Skin Cancer Articles

  • Impact of a 31-gene Expression Profiling Test for Cutaneous Melanoma on Dermatologists’ Clinical Management Decision

    Following a diagnosis of cutaneous malignant melanoma (CMM), patients are often guided for subsequent management by their dermatologist and national guideline recommendations. Based upon staging classification for CMM, guidelines recommend diagnostic tests and additional evaluation which may provide defined treatment protocols, surveillance, and follow-up.

     

  • A Randomized Trial of Broad Area ALA–PDT for Field Cancerization Mitigation in High-Risk Patients

    Actinic keratoses (AKs) are precancerous, dysplastic epidermal lesions with potential for progression to squamous cell carcinoma (SCC). A study by Criscione et al1 revealed that in a high-risk population (≥2 keratinocyte carcinomas in previous 5 years), approximately 65% of all primary SCCs arose in lesions previously diagnosed as AKs. Furthermore, it demonstrated that the risk of malignant progression of AKs to primary SCC increases over time (0.6% at 1 year and 2.6% at 4 years).1 Cellular damage and atypia seen histologically in AKs are similar to those of surrounding nonlesional skin,2,3 suggesting that skin surrounding AKs may have an increased risk of skin cancer.

     

  • Multiple Primary Melanomas Occurring Around the Same Time: A Review of Terminology and Implications

    Multiple primary melanomas (MPMs) have been reported to occur in 2-10% of melanoma patients. This study conducted a review of the literature to elucidate the definitions of terminology used to describe MPMs that were diagnosed in close temporal proximity as well as explore common risk factors. Terminology found in the literature included “concurrent”, “simultaneous” and “synchronous” with varying definitions that ranged from 0-6 months between diagnoses of the first and subsequent melanomas. Eight cases are described in chronological order, and the incidence of MPMs diagnosed around the same time were reported as 22-39%. Nevus spilus was identified as a potential risk factor for MPMs. This study highlights that MPMs are not uncommon, and clinicians should remain aware that MPMs can be diagnosed at or around the same time, warranting thorough skin exams.

 
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Case Reports

  • Basal Cell Carcinoma in the Nasal Vestibule

    Basal cell carcinomas (BCC) arise from DNA damage to cells of the basal layer of the epidermis and most commonly in areas of the skin exposed to sunlight or ultraviolet radiation. BCC is the most common skin cancer seen in humans with over 4.3 million cases reported in the United States and is responsible for 3-10% of all cancers annually. We report what we believe to be the first case of this very prevalent skin cancer arising in the nasal vestibule. The lesion was treated with Mohs micrographic surgery and required three stages to obtain histological clearance. Given the location of the tumor, Mohs surgery was chosen due to the procedure’s effectiveness for achieving the highest cure rate with the lowest incidence of tumor recurrence and for preserving as much adjacent healthy tissue as possible

     

  • Combination Topical Chemotherapy for the Treatment of an Invasive Cutaneous Squamous Cell Carcinoma

    Standard of care for squamous cell carcinoma (SCC) is usually surgical, with either excision or Mohs micrographic surgery. However, surgery may not be ideal for elderly patients with numerous lesions, who are poor surgical candidates or who refuse surgery. Topical 5-fluorouracil (5-FU) and imiquimod have been studied off-label as monotherapies in the treatment of SCC in situ with promising results. However, long-term tumor-free survival rates are still less than with surgical management.

     

  • Recurrent Squamous Cell Carcinoma Arising Within a Linear Porokeratosis

    Here we report a case of linear porokeratosis with recurrent malignant degeneration to squamous cell carcinoma (SCC) recurring six years after excision of initial SCC. A 79-year-old woman presented with a friable tumor located within a longstanding lesion on her posterior thigh. Six years prior, she was diagnosed with SCC arising within the same lesion, which had been surgically excised with negative margins. Physical examination revealed a 3.5 x 2.7 cm friable tumor on the left proximal posterior thigh.

 
View All Skin Cancer Case Reports

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NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

Support the (On)cause: A Practical Review of Supportive Oncodermatology

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iTunes Google Play Stitcher TuneIn Drs. Mario Lacouture and Adam Friedman   Cancer sucks, plain and simple. What is often overlooked is that the life saving/altering therapies often come with…

View the Latest Discoveries in Skin Cancer Research

| Skin Cancer | No Comments
Stay up-to-date on new clinical findings in Skin Cancer  View the latest articles, case reports, supplements, Podcast episodes and more!Discover the latest research in Skin Cancer: introducing the JDD Skin…

View the Latest Discoveries in Aesthetics, Anti-Aging, and Medical Dermatology

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Dermatology News

JDD Highlights

September JDD

The September issue of the Journal of Drugs in Dermatology is available now. This month, we focus on aesthetic treatments, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Read the September JDD Now

Aesthetics, Public Health, Anti-Aging, and Medical Dermatology

The September issue of the Journal of Drugs in Dermatology is available now. This month, we focus on aesthetic treatments, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Article Highlights

 

Editor's Picks

 

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

The Latest Research & Discoveries in Psoriasis, Anti-Aging, Aesthetics, and Medical Dermatology

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Dermatology News

JDD Highlights

The August issue of the Journal of Drugs in Dermatology is available now. This month, we focus on Psoriasis, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Read the JDD Now

Psoriasis, Public Health, Anti-Aging, Aesthetic, and Medical Dermatology

The August issue of the Journal of Drugs in Dermatology is available now. This month, we focus on  psoriasis with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Article Highlights

Editor's Picks

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AestheticsFeatured Articles
September 14, 2020

Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…
PhotoprotectionPodcast HighlightsSkin Cancer
September 10, 2020

NEW from the JDD Podcast: “The Science of Sun Protection”

iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…
Podcast
September 10, 2020

The Science of Sun Protection

Episode 1 of a 2-Part Series: "Sun Protection: A Review of Current Interventions and Barriers to Changing Patient Attitude and Behavior" Photoprotection works, plain and simple. Yet all too often…

View the Latest Skin of Color, Anti-Aging, Aesthetic, and Medical Dermatology Articles Now

By JDD Highlights, Skin of Color No Comments

Dermatology News

JDD Highlights

The July issue of the Journal of Drugs in Dermatology is available now. This month, we focus on Skin of Color, with special features on Anti-Aging, Aesthetic, and Medical Dermatology.
Read the JDD Now

Skin of Color, Anti-Aging, Aesthetic, and Medical Dermatology

The July issue of the Journal of Drugs in Dermatology is available now. This month, we focus on Skin of Color, with special features on Anti-Aging, Aesthetic, and Medical Dermatology.

Article Highlights

Editor's Picks

You May Also Like

Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

The Science of Sun Protection

| Podcast | No Comments
Episode 1 of a 2-Part Series: "Sun Protection: A Review of Current Interventions and Barriers to Changing Patient Attitude and Behavior" Photoprotection works, plain and simple. Yet all too often…

The Latest Research & Discoveries in Acne, Rosacea, Anti-Aging, and Medical Dermatology

By Acne, JDD Highlights, Rosacea No Comments

Dermatology News

JDD Highlights

The June issue of the Journal of Drugs in Dermatology is available now. This month, we focus on Acne and Rosacea, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Read the JDD Now

Acne, Rosacea, Public Health, Anti-Aging, Aesthetic, and Medical Dermatology

The June issue of the Journal of Drugs in Dermatology is available now. This month, we focus on Acne and Rosacea, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Article Highlights

Editor's Picks

You May Also Like

AestheticsFeatured Articles
September 14, 2020

Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…
PhotoprotectionPodcast HighlightsSkin Cancer
September 10, 2020

NEW from the JDD Podcast: “The Science of Sun Protection”

iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…
Podcast
September 10, 2020

The Science of Sun Protection

Episode 1 of a 2-Part Series: "Sun Protection: A Review of Current Interventions and Barriers to Changing Patient Attitude and Behavior" Photoprotection works, plain and simple. Yet all too often…

December Issue Highlights!

By JDD Highlights
The December 2019 JDD is here!
This month, we focus on anti-aging, aesthetics, and medical dermatology!  Take a look at our editorial highlights, editor’s picks, and more below:
  • The formation of a mnemonic that incorporates the most prevalent clinical features of PG could aid in accu­racy and speed of diagnosis in The 5 P’s of Pyoderma Gangrenosum (First Place Winner of the 9th Annual ARTE Poster Competition at ODAC)

     

     

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Derm Community
June 16, 2020

A Must-Read: The Business of Dermatology

Edited by Drs. Jeffrey S. Dover and Kavita Mariwalla, and authored by impressive experts in the field, The Business of Dermatology offers a comprehensive guide to opening, maintaining, and sustaining…
Derm CommunityODACPhotoprotectionSkin Cancer
June 1, 2020

Controversies in Photoprotection

Adam Friedman, MD, FAAD is Professor and Interim Chair of Dermatology and serves as Residency Program Director, Director of Translational Research, and Director of the Supportive OncodermatologyProgram in the Department…
Derm CommunityODACSkin Cancer
May 18, 2020

Does This Skin Cancer Really Need Mohs?

The discussion was led by Dr. Vishal Patel and Dr. Sailesh Konda, and was moderated by Dr. William Hanke. In recognition of National Skin Cancer Month, the Journal of Drugs…