Aesthetics

Safety, Tolerability, and Efficacy of Repeat-Dose Injections of IncobotulinumtoxinA in the Treatment of Upper Facial Lines: Results from a Prospective, Open-Label, Phase III Study

By April 29, 2020 No Comments

Dermatology News

"Safety, Tolerability, and Efficacy of Repeat-Dose Injections of IncobotulinumtoxinA in the Treatment of Upper Facial Lines: Results from a Prospective, Open-Label, Phase III Study"

IncobotulinumtoxinA (Xeomin/Xeomeen/Bocouture/XEOMIN Cosmetic; botulinum toxin type A free from complexing proteins [150 kDa]; Merz Pharmaceuticals GmbH) is indicated worldwide for the correction of glabellar frown lines (GFL) and in Europe additionally for lateral periorbital lines (LPL; crow’s feet) and upper facial lines (UFL; ie, simultaneous treatment of GFL, LPL, and horizontal forehead lines [HFL]).1

The efficacy of incobotulinumtoxinA in the treatment of multiple or singular facial areas has been extensively demonstrated.2-10 With the recent surge in interest for a more holistic approach, consisting of combined treatment of GFL, HFL, and LPL in a single treatment session, there is a need for demonstrating safety and efficacy for such procedures.

This study provides strong evidence for the safety and tolerability of repeat-dose treatments with incobotulinumtoxinA in UFL (GFL, 20 U; HFL, 10-20 U; LPL, 24 U). A stable safety profile was demonstrated during prolonged administration and a noteworthy trend to better tolerability with continued use of incobotulinumtoxinA was established

Read More

You May Also Like

The Latest on Oncodermatology, Psoriasis, Atopic Dermatitis & More

| JDD Highlights | No Comments
The May issue of the Journal of Drugs in Dermatology is available now. This month, we focus on Skin Cancer, with special features on Public Health, Atopic Dermatitis, Psoriasis, and…

Current Issue Highlights

| JDD Highlights | No Comments
New Dermatological Research is available now- view this months' JDD features, case reports, and research below: Dermatologists respond regarding the impact of COVID-19 and examine the potential impact of drugs…

New Research Available Now

| JDD Highlights | No Comments
The latest research in Dermatology is available online now: take a look at JDD's March 2020 content highlights: Azelaic acid 15% foam may be an efficacious therapy for rosacea while…