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Probiotics Supplementation Improves Quality of Life, Clinical Symptoms, and Inflammatory Status in Patients With Psoriasis

By July 19, 2025No Comments
Journal of Drugs in Dermatology JDD Article About Probiotics Supplementation Improves Quality of Life, Clinical Symptoms, and Inflammatory Status in Patients With Psoriasis

Can Probiotics Help Psoriasis? This Study Says Yes—And Here’s Why You Should Pay Attention

Could your next psoriasis treatment plan include probiotics? A randomized, double-blind, placebo-controlled trial published in JDD’s June 2022 issue suggests it might be time to think beyond the skin.

Researchers found that patients with psoriasis who took a multi-strain probiotic supplement for two months saw significant improvements in their Psoriasis Area and Severity Index (PASI) scores and quality of life. Even more compelling? Markers of inflammation and cardiovascular risk dropped notably in the probiotic group compared to placebo.

While the gut-skin connection has been theorized for years, this study adds real clinical weight to the idea that targeting the microbiome may help reduce systemic inflammation and improve psoriasis outcomes.

What This Means for Your Practice:
It’s time to consider the gut in your psoriasis treatment conversation. Though probiotics aren’t a stand-alone solution, they may be a low-risk, adjunctive tool to support your patients’ skin, systemic health, and overall well-being.

Take Action:
Start asking your patients about their gut health, and stay tuned for larger trials that may redefine your approach to chronic inflammatory skin disease.

J Drugs Dermatol. 2022;21(6):637-644. doi:10.36849/JDD.6237 

Blog write-up assisted by AI