introductionNemolizumab is a humanized monoclonal antibody directed against the interleukin (IL)-31 receptor alpha chain (IL-31RA) that blocks signaling from neuroimmune cytokine IL-31. While IL-31 was first thought to be primarily…
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INTRODUCTIONPsoriasis is a significant health and economic burden. In the United States, the prevalence of psoriasis is estimated to be 7.4 million, which accounts for ~2.2% of the population, with…
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INTRODUCTIONCutaneous warts are benign growths on the skin that can affect various parts of the body, most commonly the face, hands, and feet.1 Warts affect 10% of the population and…
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INTRODUCTIONLichen planus is an auto-inflammatory skin disorder marked by intensely pruritic, violaceous papules that commonly affect the extremities of middle-aged adults.1 Though a clear pathogenic mechanism remains unknown, some of…
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INTRODUCTIONPorokeratosis is a rare group of acquired or hereditary dermatoses characterized by pruritic, linear, or annular plaques with a keratotic border.1,2 Although the pathophysiology remains unclear, the development of porokeratosis…
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INTRODUCTIONAlopecia areata (AA) was once considered a mere cosmetic condition. Now, we know that AA is a disease that profoundly impacts patients' lives.1 Alopecia areata not only causes psychosocial distress…
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INTRODUCTION Androgenetic alopecia (AGA) is a hereditary, androgen-dependent, dermatological disorder characterized by miniaturization of scalp hair. It is the most common type of progressive hair loss with varying severity and…
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INTRODUCTION Psoriasis is a chronic inflammatory disease that affects approximately 8 million adults in the United States.1 It is characterized by sharply demarcated, erythematous plaques with overlying scales that can…
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INTRODUCTION Psoriasis is a chronic inflammatory disease that affects approximately 8 million adults in the United States.1 It is characterized by sharply demarcated, erythematous plaques with overlying scales that can…
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INTRODUCTIONOnychomycosis is an infection of the nail bed or nail plate by fungal organisms. These organisms are predominantly dermatophytes and less commonly yeasts, but recent research revealed an increasing prevalence…
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It has been known for decades that the sequential topical use of the vitamin D3 analog calcipotriene (Cal) and the corticosteroid betamethasone dipropionate (BD) has been shown to provide greater…
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INTRODUCTIONPhotoaging is the greatest contributing factor to facial aging1 and is among the most prevalent skin conditions in the United States (US).2 Typically defined as extrinsic aging of the skin…
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