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Neoadjuvant Sonidegib for the Management of Locally Advanced Basal Cell Carcinoma: A Case Report

By February 24, 2025No Comments
Journal of Drugs in Dermatology JDD Article About Neoadjuvant Sonidegib for the Management of Locally Advanced Basal Cell Carcinoma: A Case Report

Sonidegib for laBCC: A Neoadjuvant Game Changer?

Neoadjuvant Hedgehog Pathway Inhibitors (HPIs) are reshaping the approach to locally advanced basal cell carcinoma (laBCC), but tolerability remains a concern. A recent case highlights successful tumor reduction with sonidegib before Mohs surgery—achieving optimal results with minimal side effects. Could this be the key to better outcomes in cosmetically sensitive areas?