Issue Archive
August 2012 | Volume 11 | Issue 8
Editorials
Original Articles
The Safety of Ustekinumab in Psoriasis
Ustekinumab is effective in the treatment of a variety of autoimmune conditions including psoriasis. As a relatively new therapeutic agent, its long-term effects are still under investigation. Short-t...
Read MoreJAK Inhibitors in Psoriasis: A Promising New Treatment Modality
Background: Inflammatory cytokines play a crucial role in the pathophysiology of psoriasis. New therapies are targeting Janus kinases (JAKs), enzymes involved with transduction of cytokine receptor si...
Read MoreDigital Videography Assessment of Patients' Experiences Using Adapalene-Benzoyl Peroxide Gel in the Treatment of Acne Vulgaris
Background: Acne profoundly affects patients' lives, but the effect of treatment is not fully characterized.
Objective: The purpose of this study was to explore patients' experiences and viewpoi...
Read MoreA Randomized Controlled Study of Combination Therapy With Alefacept and Narrow Band UVB Phototherapy (UVB) for Moderate to Severe Psoriasis: Efficacy, Onset, and Duration of Response
Background: Alefacept is an effective intermittent treatment for psoriasis that can provide long-lasting remissions. Combination therapy with narrow-band ultraviolet B (nbUVB) phototherapy may enhance...
Read MoreTreatment of Nail Psoriasis With TNF-α or IL12/23 Inhibitors
Nail psoriasis appears to be an important source of psoriatic morbidity through physical impairment, pain, and cosmetic disturbances. Conventional treatment is often unsatisfactory. A systematic revie...
Read MoreUstekinumab Improves Health-Related Quality of Life in Korean and Taiwanese Patients With Moderate to Severe Psoriasis: Results from the PEARL Trial
Background: The PEARL study showed that the proportion of psoriasis patients achieving the primary endpoint (at least 75% improvement from baseline to week 12 in the Psoriasis Area and Severity Index)...
Read MoreOpen Label Study to Evaluate the Efficacy of Re-Treatment With Etanercept in Patients With Psoriasis
Background: Etanercept has been used to treat chronic plaque psoriasis. Previously reported data demonstrated that some patients experienced secondary failure and frequently rotational-switch therapy ...
Read MoreTrends in Older Adult Psoriasis Outpatient Health Care Practices in the United States
Background: Psoriasis is among the top dermatologic diagnoses for older adult patients, and the number of older adult psoriasis patients is expected to rise.
Purpose: To characterize trends in o...
Read MoreEfficacy and Tolerability of Two Commercial Hyperpigmentation Kits in the Treatment of Facial Hyperpigmentation and Photo-Aging
Background: Hyperpigmentary disorders are common aesthetic skin conditions that can be very concerning to patients and both challenging and time-consuming for the physician to treat. Several companies...
Read MoreTreatment With a Novel Topical Nanoemulsion (NB-001) Speeds Time to Healing of Recurrent Cold Sores
Background: Current topical therapies for cold sores are only marginally beneficial due to poor skin penetration. We assessed the safety and efficacy of a novel topical antiviral nanoemulsion (NB-001)...
Read MoreThe Use of Cyclosporine in Dermatology
Cyclosporine is an immunosuppressive drug that acts selectively on T-cells by inhibiting calcineurin phosphorylase. It has been used in dermatology since its approval for US Food and Drug Administrati...
Read MoreReconstruction of a Lower Eyelid Defect With a V to Y Island Flap
Repair of full thickness defects in the lower eyelid following extirpation of malignant tumors presents a challenge to the reconstructive surgeon. There are several techniques to choose from, dependi...
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Features
RESIDENT ROUNDS: PART I
History of Howard University Hospital Department of Dermatology and Residency ProgramResident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes three sections: (1) a program spotlight, hi...
Read MoreRESIDENT ROUNDS: PART II
Disorders of PigmentationRESIDENT ROUNDS: PART III
Case Report: Vogt-Koyanagi-Harada Disease in an African-American FemaleNEWS, VIEWS, & REVIEWS
Chronic Ulcers: When to Consider Malignancy?PIPELINE PREVIEWS
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MoreCLINICAL TRIAL REVIEW
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
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Case Reports
Treatment of Psoriasis and Long-term Maintenance Using 308 nm Excimer Laser, Clobetasol Spray, and Calcitriol Ointment: A Case Series
Psoriasis is a chronic inflammatory skin disease that is characterized by thickened red plaques covered with silvery scales. Excimer laser therapy is a cutting-edge advancement in UVB phototherapy. In...
Read MoreUstekinumab for Treatment of Plaque Psoriasis in a Patient With Down Syndrome
Down syndrome (DS) is the most common chromosomal disorder and a major cause of mental retardation. Down syndrome phenotype is complex and may present a combination of dysmorphic features, congenital ...
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Supplements
The New Face of Fillers: A Multi-Specialty CME Initiative (Part II of II)
Part II of this two-part supplement brings together experts from the U.S., France, Germany, and Italy to discuss state-of-the-art soft tissue fillers in a fair-balanced, CME-accredited format. It incl...
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