Issue Archive
February 2012 | Volume 11 | Issue 2
Original Articles
Ustekinumab: A Review in the Treatment of Plaque Psoriasis and Psoriatic Arthritis
Psoriasis is a complex, multigenic immune/inflammatory-mediated disorder that variably affects the skin, nails, and joints. In September 2009, ustekinumab (Stelara®), a monoclonal antibody that ta...
Read MoreIdentification of the Leprosy Agent Mycobacterium lepromatosis in Singapore
Background: A new leprosy-causing species, namely Mycobacterium lepromatosis, was discovered recently to be the cause of diffuse lepromatous leprosy (DLL) in Mexico. It is unknown whether this organi...
Read MoreShort-Term Combination Therapy and Long-Term Relapse Prevention in the Treatment of Severe Acne Vulgaris
Few long-term treatment regimens for severe acne vulgaris have been investigated in clinical trials. Data were combined from two consecutive, randomized, double-blind, controlled studies to evaluate t...
Read MoreTransepidermal Water Loss (TEWL) and Corneometry With Hydrogel Vehicle in the Treatment of Atopic Dermatitis: A Randomized, Investigator-Blind Pilot Study
Disruption of the epidermal barrier, as indicated by a reduction in skin hydration and an increase in transepidermal water loss (TEWL) is a feature of atopic dermatitis (AD). Novel formulations of der...
Read MoreBilateral Axilla Hair Removal Comparing a Single Wavelength Alexandrite Laser With Combined Multiplexed Alexandrite and Nd:YAG Laser Treatment From a Single Laser Platform
Background/Objectives: This study compares the efficacy, safety, and side-effect profile of three different firing modes in a single laser emitting both dual-wavelength multiplexed laser pulses and si...
Read MorePatient Satisfaction and Complications Following Laser Hair Removal in Ethnic Skin
Background: Laser hair removal (LHR) is increasingly popular for the treatment of unwanted hair. To date, there have been few studies to evaluate patient satisfaction and complications after LHR among...
Read MoreA Randomized, Prospective Trial Evaluating Surgeon Preference in Selection of Absorbable Suture Material
This study is the first double-blinded, randomized comparison of two absorbable sutures. To better understand product characteristics and surgeon preference, we conducted a study of two similar-appear...
Read MoreA Facial Marker in Facial Wasting Rehabilitation
Background: Facial lipoatrophy is one of the most distressing manifestation for HIV patients. It can be stigmatizing, severely affecting quality of life and self-esteem, and it may result in reduced ...
Read MoreEfficacy and Tolerability Assessment of a Topical Formulation Containing Copper Sulfate and Hypericum perforatum on Patients With Herpes Skin Lesions: A Comparative, Randomized Controlled Trial
Background: Topical Acyclovir has moderate efficacy on recurrent HSV symptoms, requiring repeat applications for several days. Topical Dynamiclear, which requires only a single dose application, may p...
Read MoreComparison of Four Botulinum Neurotoxin Type A Preparations in the Treatment of Hyperdynamic Forehead Lines in Men: A Pilot Study
Background:Botulinum neurotoxin type A (BTXA) offers a minimally invasive approach for the treatment of facial rhytides and has been well accepted by male patients. However, few comparative studies ab...
Read MoreOver-the-Counter Topical Skincare Products: A Review of the Literature
Topical "anti-aging" products, with their seemingly limitless list of ingredients, make extensive claims to reduce wrinkles, fine lines, and sun damage, among others. Sales in the United States alone ...
Read MoreBack to Basics: Reconstruction of Defects on the Lower Half of the Nose
Background: Surgical reconstruction of defects on the lower half of the nose mandates special considerations. Simple excision and suturing might cause a depressed scar and nostril flaring. Hence, the ...
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Features
Program Spotlight: Georgia Health Sciences University
Resident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes three sections: (1) a program spotlight, hi...
Read MoreAmyloidoses of Dermatologic Significance
Gianotti-Crosti Syndrome Associated with Hepatitis A and Influenza Vaccination
Pedunculated Melanoma
Novel Therapies for the Treatment of Metastatic Melanoma
PIPELINE PREVIEWS
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MoreCLINICAL TRIAL REVIEW
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
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Case Reports
Bullous Pemphigoid Associated With Renal Cell Carcinoma and Invasive Squamous Cell Carcinoma
Background: Bullous pemphigoid (BP) is an acquired, autoimmune, sub-epidermal blistering disease. The incidence of both BP and internal malignancy increases with age, yet the relationship between BP a...
Read MoreLeprosy-Like Illness in a Patient With Mycobacterium lepromatosis From Ontario, Canada
Here we present the first case of a patient from Ottawa Canada, presenting with leprosy-like illness associated with Mycobacterium lepromatosis. The patient had no history of travel to leprosy-endemic...
Read MoreMultifocal, Fixed-Drug Eruption Masqueradingas Recurrent Erythema Multiforme
Fixed drug eruptions often have a characteristic appearance, which, when correlated with the clinical history, can be easily identified. However, multifocal fixed drug eruptions, especially the non-pi...
Read MoreAcitretin-Induced Poliosis With Concurrent Alopecia
Acitretin, a metabolite of the aromatic retinoid etretinate, has been utilized successfully in the treatment of psoriasis since the late 1980s. Of the oral retinoids available, etretinate and acitreti...
Read MoreA Myxoid Neurothekeoma of the Nose
Neurothekeoma is a rare neoplasm assigned to the broad category of benign peripheral nerve sheath tumors. Its cell of origin is still unknown, but most ultrastructural and immunohistochemical studies ...
Read MoreTreatment of Ulcerated Necrobiosis Lipoidica With Intravenous Immunoglobulin and Methylprednisolone
The authors report a female patient with recalcitrant ulcerated necrobiosis lipoidica (NL) that was resistant to numerous systemic agents and who responded to treatment with intravenous immunoglobulin...
Read MorePaclitaxel-Associated Subungual Pyogenic Granuloma: Report in a Patient With Breast Cancer Receiving Paclitaxel and Review of Drug-Induced Pyogenic Granulomas Adjacent to and Beneath the Nail
Subungual and periungual pyogenic granuloma occur in association with certain systemic medications. Paclitaxel is an antitumor drug of the taxane family used in the management of breast cancer. Taxane...
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