Issue Archive
January 2012 | Volume 11 | Issue 1
Editorials
Original Articles
Two Randomized, Controlled, Comparative Studies of the Stratum Corneum Integrity Benefits of Two Cosmetic Niacinamide ⁄ Glycerin Body Moisturizers vs. Conventional Body Moisturizers
Background and Objective: Despite numerous body moisturizers being available, cosmetic xerosis continues to be a leading skin problem for consumers. We performed two 35-day studies to evaluate the abi...
Read MoreApplication of a Topical Biomimetic Electrical Signaling Technology to Photo-Aging: A Randomized, Double-Blind, Placebo-Controlled Trial of a Galvanic Zinc-Copper Complex
Background: The first signs of facial skin photo-aging often occur in the skin of the periorbital area and include sagging, loss of firmness and definition, and sallowness. Epidermal wounds have been ...
Read MoreResults of a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a Botulinum Toxin Type A Topical Gel for the Treatment of Moderate-to-Severe Lateral Canthal Lines
Background: Injections of botulinum toxin type A are commonly used to treat facial wrinkles; however, undesirable effects are associated with injections (e.g., pain, bruising, ptosis, immunogenicity, ...
Read MoreNonanatomic Free Cartilage Batten Grafting With Second Intention Healing for Defects on the Distal Nose
Background: Defects of the distal nose, particularly the nasal ala, pose a reconstructive challenge due to the lack of loose adjacent tissue and proximity to a free margin.
Objective: We report...
Read MoreSplit-Face Study of Topical 23.8% L-Ascorbic Acid Serum in Treating Photo-Aged Skin
Background: L−ascorbic acid has been widely used to treat photo-aged skin. However, its aqueous formula is prone to oxidation. Therefore, a new formula that contains 23.8% L−ascorbic acid ...
Read MoreTreatment of Focal Axillary Hyperhidrosis Using a Long-Pulsed Nd:YAG 1064 nm Laser at Hair Reduction Settings
Background and Objective: Axillary hyperhidrosis is a rather common idiopathic disorder of the eccrine sweat glands, which can interfere with daily activities and cause significant social distress. Th...
Read MoreA Randomized, Double-Blind, Controlled Comparative Trial of the Anti-Aging Properties of Non-Prescription Tri-Retinol 1.1% vs. Prescription Tretinoin 0.025%
Vitamin A and its derivatives (commonly termed retinoids) are widely used in topical anti-aging products. Certain retinoids such as retinol and its esters are available without a prescription, while o...
Read MoreComparison of the Effects of Contractubex® Gel in an Experimental Model of Scar Formation in Rats: An Immunohistochemical and Ultrastructural Study
Background: Contractubex® gel, a commercial treatment for scars, consists of a mixture of onion extract (cepea extract), heparin sodium, and allantoin. It exerts a softening and smoothing effect o...
Read MoreSafety and Efficacy Evaluation of Tretinoin Cream 0.02% for the Reduction of Photodamage: A Pilot Study
Background: Clinical studies as well as histologic data maintain that tretinoin improves the appearance of photodamage; however, the long-term benefits of tretinoin 0.02% in moderate to severe photoda...
Read MoreA Review of Protocols for 308 nm Excimer Laser Phototherapy in Psoriasis
Background: 308 nm excimer laser phototherapy is efficacious in the treatment of localized psoriasis. Different approaches regarding dose fluency, number of treatments, and maintenance have been util...
Read MoreThe Hatchet and Bilobed Flaps Revisited: Shedding New Light on Traditional Concepts
Background: The bilobed and hatchet flaps are well-accepted reconstructive options for the correction of defects of the lower third of the nose. Optimal utilization of these flaps depends on understan...
Read MoreNews, Views & Reviews
News, Views and Reviews provides focused updates, topic reviews and editorials concerning the latest developments in dermatologic therapy....
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Features
Use of Blunt Tipped Cannulas for Soft Tissue Fillers
In the US, soft tissue fillers are currently administered using sharp, hypodermic needles. The choice in length and gauge of needle is determined by the injector's preferences, as well as the physical...
Read MoreResident Rounds: Part 1
Program Spotlight: The Mayo Clinic Dermatology Residency Training ProgramResident Rounds is a section of the JDD dedicated to highlighting various dermatology departments with residency training programs. Resident Rounds includes three sections: (1) a program spotlight, hi...
Read MoreResident Rounds: Part II
Skeletal and Radiographic Findings Associated With Dermatological DisordersResident Rounds: Part III
Necrobiotic Xanthogranuloma of the ExtremitiesTruth or Fiction: Risk Factors for Childhood Atopic Dermatitis
Atopic dermatitis is increasing in prevalence throughout the developed world, in parallel with asthma and hay fever. The reasons for the increase remain unclear. As a practical question, it is valuabl...
Read MorePIPELINE PREVIEWS
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MoreClinical Trial Review
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
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Case Reports
Topical Bimatoprost for the Treatment of Eyebrow Hypotrichosis
Topical bimatoprost was FDA approved in December of 2008 for the treatment of eyelash hypotrichosis. Since its approval, some physicians have advocated the use of bimatoprost "off label" for hair grow...
Read MorePersistent Erythematous Lesion of the Vulva: A Diagnostic and Treatment Challenge
The painful, erythematous and eroded vulva often proves to be a diagnostic problem both clinically and histologically. Its differential diagnosis includes both non-neoplastic and neoplastic...
Read MoreTransient Improvement in Chronic Psoriasis After Treatment of TNF-α Blocker Induced Disseminated M. Tuberculosis Infection
Improvement in psoriasis after treatment of reactivated latent tuberculosis following initiation of TNF-α inhibitor therapy has yet to be described in the literature. The authors present a case o...
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Supplements
Emervel: Full-Face Rejuvenation With a Range of Customized Hyaluronic Acid Fillers
Emervel: Full-Face Rejuvenation With a Range of Customized Hyaluronic Acid Fillers This supplement to the Journal of Drugs in Dermatology discusses a new range of hyaluronic acid fillers suited for va...
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