Issue Archive
November 2010 | Volume 9 | Issue 11
Editorials
The Role of Complement in Dendritic Cell (DC ) Control of T-cell Subsets
This section of the Journal of Drugs in Dermatology (JDD) is dedicated to Dendreon’s Provenge (Sipuleucel-T), the first therapeutic DC vaccine proven effective and approved by the United States...
Read More
Original Articles
Ultrapulsed Fractional CO2 Laser for the Treatmentof Post-traumatic and Pathological Scars
Background and Objective: Scar management is a long-term process. A variety of modalities have been employed and, depending on scar type, treatment may be invasive and/or conservative. The purpose of...
Read MoreTreatment of Tattoos With a 755-nm Q-switched Alexandrite Laser and Novel 1064 nm and 532 nm Nd:YAG Laser Handpieces Pumpedby the Alexandrite Treatment Beam
Background: Multi-colored and even black tattoos often require more than one wavelength to remove the target pigment. The authors report here a novel alexandrite laser with two Nd:YAG laser handpiece...
Read MoreTreatment of Facial Acne Scars in Asian Skin With the Single-spot, 2940-nm Er:YAG Dual-mode Laser
Modalities for the treatment of atrophic facial acne scars have been studied extensively. One, an erbium:yttrium-aluminum garnet (Er:YAG) laser device that generates both short, ablative pulses of hig...
Read MorePhotodynamic Therapy With Methylaminolevulinate 80 mg/g Without Occlusion Improves Acne Vulgaris
Background: Photodynamic therapy (PDT) with methylaminolevulinate (MAL) under occlusion is effective for the treatment of acne vulgaris but is associated with significant phototoxic side effects. Ob...
Read MoreLasers for Scars: A Review and Evidence-Based Appraisal
Numerous treatment modalities are available for scar management depending upon scar characteristics, age and patient expectations. The focus of this article is to review commonly used nonsurgical meth...
Read MoreTH 17 is Involved in the Remarkable Regression of Metastatic Malignant Melanoma to Topical Diphencyprone
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-deriv...
Read MoreA Potential Role for Complement in Immune Evasion by Mycobacterium leprae
Lepromatous leprosy is a model of immune evasion wherein pathogen-specific IL-10-secreting T cells and concomitant failure of Th-1 immunity permit uncontrolled proliferation of the intracellular patho...
Read MoreDendritic Cells and T Cells in Immunotherapy
Autologous cellular immunotherapies have been used experimentally in humans to treat many types of cancer. These therapies are divided into two principal types: active cellular immunotherapies that re...
Read MoreTreatment of 2,453 Acne Vulgaris Patients Aged 12–17 Years With the Fixed-dose Adapalene-benzoyl Peroxide Combination Topical Gel: Efficacy and Safety
Acne vulgaris is a common disease in adolescents, and early treatment may minimize its physical and psychological effects. A fixeddose combination gel of adapalene 0.1% and benzoyl peroxide 2.5% (adap...
Read MoreChanges in Rosacea Comorbidities and Treatment Utilization Over Time
Background: Rosacea is a chronic skin condition that requires lifelong treatment. Given the rise in antibiotic-resistant bacteria, many physicians are re-evaluating their use of antibiotics for long-t...
Read MoreDoxycycline and Minocycline for the Management of Acne: A Review of Efficacy and Safety With Emphasis on Clinical Implications
A significant number of patients with moderate-to-severe inflammatory acne are candidates for oral antibiotic therapy. Use of tetracycline for acne has yielded to second-generation molecules doxycycli...
Read MoreUpdate on the Pathogenesis, Genetics and Medical Treatment of Patterned Hair Loss
Androgenic alopecia (AGA), or pattern hair loss, is a common condition that affects both men and women has been gradually increasing. The discovery of the androgen receptor (AR) gene and related genes...
Read MoreClinical Trial Review
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs undergoing clinical testing. It is our goal to inform the reader of the status of select drug trials ...
Read MoreNews, Views & Reviews
News, Views and Reviews provides focused updates, topic reviews and editorials concerning the latest developments in dermatologic therapy....
Read MorePipeline Previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from th...
Read More
Case Reports
Treatment of CO2 Laser Induced Hypopigmentation With Ablative Fractionated Laser Resurfacing: Case Report and Review of the Literature
Background: The carbon dioxide laser (CO2) has been proven to be an effective device for the treatment of photoaging. However, it is associated with adverse side effects including prolonged erythema,...
Read MoreBlue Foot: A Second Case of “Tattoo Blow-out†Pigment Spread Successfully Treated With the QS-Nd:YAG Laser
The “tattoo blow-out†phenomenon occurs when tattoo pigments spread outside the border of a tattoo. It is thought to occur when ink is injected too deeply. A healthy 36-year-old female pr...
Read MoreCTLA 4-induced Splenomegaly and A Review of the Literature Pertaining to Autoimmune Complications of Therapy
CTLA4-blocking antibodies induce tumor regression in a subset of patients with metastatic melanoma by optimizing T-cell activity to fight the malignant cells. In addition to therapeutic benefits, CTL...
Read MoreCase Report: Cutaneous Nontuberculous Mycobacterial Abscesses Associated With Insulin Injections
Nontuberculous mycobacterial (NTM) infections are on the rise and often cause skin diseases that are misdiagnosed. The authors present three cases of atypical mycobacterial infections in insulin-depen...
Read More
