Issue Archive
July 2009 | Volume 8 | Issue 7
Original Articles
Pathogenesis of Acne Vulgaris: Recent Advances
Acne vulgaris is the most common disorder seen in ambulatory dermatology practice. Acne causes signifi cant morbidity and the direct costs associated with it exceed $2.2 billion per year in the Unite...
Read MoreComparative Efficacy and Safety Results of Two Topical Combination Acne Regimens
Combination therapy has become the standard for the management of acne, particularly for moderate-to-severe cases. Among these combinations, those regimens containing benzoyl peroxide (BPO), clindamy...
Read MoreThe Development and Optimization of a Fixed Combination of Clindamycin and Benzoyl Peroxide Aqueous Gel
Fixed combination products of clindamycin 1% (as 1.2% clindamycin phosphate) and benzoyl peroxide (BPO) 5% are commonly used in the treatment of acne vulgaris. Although any given topical acne product...
Read MoreA Multicenter Study of Topical Azelaic Acid 15% Gelin Combination With Oral Doxycycline as Initial Therapy and Azelaic Acid 15% as Maintenance Monotherapy
This two-phase, multicenter study was undertaken to examine the safety and effi cacy of combination therapy with oral doxycycline and topical azelaic acid (AzA) 15% gel in moderate-to-severe papulopus...
Read MoreTretinoin Microsphere Gel Pump 0.04% Versus Tazarotene Cream 0.05% in the Treatment of Mildto-Moderate Facial Acne Vulgaris
This 12-week, single-center, investigator-blinded, randomized, parallel-design study assessed the safety and effi cacy of tretinoin microsphere gel 0.04% delivered by pump (TMG PUMP) to tazarotene cr...
Read MoreAdvancement in Benzoyl Peroxide-Based Acne Treatment: Methods to Increase Both Efficacy and Tolerability
Background: Antibiotic resistance of Propionibacterium acnes (P. acnes) is a growing phenomenon in the wake of widespread use of topical and systemic antibiotics for acne vulgaris. Benzoyl peroxide h...
Read MoreAnti-Inflammatory Dose Doxycycline in the Treatment of Rosacea
Anti-infl ammatory dose doxycycline (ADD), which is the administration of doxycycline 40 mg extended-release capsule once daily, is the only oral therapy approved by the United States Food and Drug A...
Read MoreNews, Views and Reviews
Pipeline Previews
Clinical Trial Review
Case Reports
Treatment of Acne Vulgaris Using Blue Light Photodynamic Therapy in an African-AmericanPatient
Background: Studies indicate photodynamic therapy is an effective treatment of infl ammatory acne lesions on patients with Fitzpatrick skin types 1–3. There is a lack of evidence in the litera...
Read More
Supplements
Genomics of Skin Aging: Practical Applications
This supplement to the Journal of Drugs in Dermatology is sponsored by P&G Beauty & Grooming....
Read MoreUnderstanding Metabolic Pathways for Skin Anti-Aging
Global gene expression profiling provides a useful means to identify key aspects of the skin aging process, and provides information to help develop new skin technologies. Important aspects of skin ag...
Read MoreGenomic-Driven Insights Into Changes in Aging Skin
Like all tissues, the skin ages due to the passage of time (chronologic aging). However, skin is also exposed to external insults, such as sunlight. Aging due to chronic sun exposure (photoaging) is c...
Read MoreFrom Bench to Beauty Counter: Using Genomicsto Drive Technology Development for Skin Care
The skin is not only the body’s largest organ but is widely considered to be the sentinel organ of the human body as it is often the first line of defense from environmental insults. Acting as b...
Read MorePractical Applications of Genomics Research forTreatment of Aging Skin
Skin aging integrates the impact of extrinsic skin insults (e.g., ultraviolet [UV] light, etc.) with chronological, genetically programmed decreases in cellular function. A genomic study of aged skin ...
Read More
