Issue Archive
June 2007 | Volume 6 | Issue 6
Original Articles
The Propionibacterium acnes Genome: From the Laboratory to the Clinic
The genome of Propionibacterium acnes, the microbe presumed to be at least partially etiologic for the development of acne, has recently been decoded. The genome supports long-standing concepts regar...
Read MorePediatric Acne: Clinical Presentations, Evaluation, and Management
Acne vulgaris can be easy to diagnose yet difficult to evaluate and manage, especially when it presents in infancy and childhood. The differential diagnosis of acne varies by age and, in some cases, ...
Read MoreA Closer Look at Truncal Acne Vulgaris: Prevalence, Severity, and Clinical Significance
Data is very limited on the demographics, epidemiology, grading, and management of truncal acne vulgaris. In this study completed in 5 cities across the US, 696 patients were assessed to evaluate the...
Read MoreClinical Safety and Efficacy Studies of a Novel Formulation Combining 1.2% Clindamycin Phosphate and 0.025% Tretinoin and for the Treatment of Acne Vulgaris
Clindamycin phosphate 1.2% and tretinoin 0.025% gel (CLIN/RA gel [ZIANAâ„¢ Gel]) is a novel topical combination agent approved by the FDA for the treatment of acne vulgaris in patients 12 years o...
Read MoreStudy Results of Benzoyl Peroxide 5%/Clindamycin 1% Topical Gel, Adapalene 0.1% Gel and Use in Combination for Acne Vulgaris
Combination therapy is the standard of care in the management of acne vulgaris. It is essential to treat as many aspects of acne pathogenesis as possible. Due to increasing insensitivity of Propionib...
Read MoreA Comparative Review of the Efficacy and Tolerability of Retinoid-Containing Combination Regimens for the Treatment of Acne Vulgaris
Many physicians regularly prescribe combination therapy involving a retinoid for their acne patients. The most common retinoid-containing regimens include either oral antibiotics or topical benzoyl p...
Read MoreTolerability Comparison of Adapalene Gel, 0.3% versus Tazarotene Cream, 0.05% in Subjects with Healthy Skin
Background: Topical retinoids, including adapalene and tazarotene, are a primary treatment choice for patients with acne. Adapalene is currently marketed in a 0.1% concentration in gel and cream form...
Read MoreCombined Effect of Anti-inflammatory Dose Doxycycline (40-mg Doxycycline, USP Monohydrate Controlled-Release Capsules) and Metronidazole Topical Gel 1% in the Treatment of Rosacea
Research into the pathophysiology of rosacea suggests a central role for inflammatory mediators such as nitric oxide (NO), reactive oxygen species (ROS), and matrix metalloproteinases (MMPs). Effectiv...
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Features
Case Reports
Efalizumab-Associated Lymphoproliferative Disease
Efalizumab is an immunosuppressive agent that has been approved for the treatment of psoriasis. There has been mounting evidence that efalizumab may be associated with lymphoma/malignancy development...
Read MoreClearance of Lentigines in Japanese Men with the Long-Pulsed Alexandrite Laser
Background: 5-fluorouracil (5-FU) and imiquimod creams are accepted topical therapies for actinic keratosis (AK). Both are associated with a prolonged course of treatment with an inflammatory respons...
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Supplements
The Science of Next Generation Anti-Aging Cosmeceuticals
This supplement to the Journal of Drugs in Dermatology was supported by Dior...
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