Issue Archive
May 2026 | Volume 25 | Issue 5
Editorials
Benzoyl Peroxide and Malignancy Risk: A Systematic Review and Meta-analysis of Over 4 Million Patients
Thermal Imaging for Cryotherapy Documentation in Dermatology Practice
Malignancy Risk in Autoimmune Blistering Disorders: A Retrospective Cohort Study
Chronic Kidney Disease and Postoperative Complications Following Mohs Surgery: A Retrospective Cohort Study
Original Articles
Efficacy and Safety of Topical Metformin vs Kligman Formula in the Treatment of Melasma: A Split-Face Study
Background: Melasma is an acquired pigmentary disorder characterized by symmetrical hyperpigmented macules and patches on sun-exposed areas, primarily the face. Kligman's formula, or "triple combinati...
Read MoreMalassezia Folliculitis Presentation, Diagnosis, and Treatment: A Review of "Fungal Acne"
Background: Malassezia folliculitis (MF), commonly referred to as "fungal acne" is a dermatological condition caused by colonization of the commensal fungus Malassezia, which turns pathogenic under ce...
Read MoreAdvances in Gentle Polymeric Cleansing Technologies
Modern skin cleansers have evolved from basic soaps to advanced cleansing formulations that also provide moisturization and skin barrier support. Surfactants work by emulsifying oils and reducing surf...
Read MoreSafety and Efficacy of Aminolevulinic Acid 20% Topical Solution Activated by Blue Light for Facial Cutaneous Squamous Cell Carcinoma in situ
Background: Squamous cell carcinoma in situ (isSCC) is an early-stage cutaneous malignancy that requires effective treatment to prevent progression to invasive SCC. Aminolevulinic acid photodynamic th...
Read MoreLonger Pembrolizumab Therapy Reduces Mortality in Stage III and IV Melanoma: A TriNetX Study
Background: Melanoma is the leading cause of skin-cancer-related mortality worldwide. Anti-programmed cell death protein-1 therapies, including pembrolizumab, play a critical role in treating advanced...
Read MoreEfficacy and Safety of Cosibelimab for Advanced Cutaneous Squamous Cell Carcinoma: An Expert Consensus Panel
Background: Cutaneous squamous cell carcinoma (cSCC) represents a significant clinical challenge in patients with locally advanced (laCSCC) or metastatic (mCSCC) disease who are not candidates for sur...
Read MoreWeight Loss and Its Impact on Soft Tissue
Background: Rapid and intentional weight loss can result from bariatric surgery, pharmacologic agents such as glucagon-like peptide-1 receptor agonists, and intensive lifestyle changes. Although effec...
Read MoreClinical Methodology to Evaluate the Efficacy of a Topical Cosmetic Eye Formulation on the Appearance of Dynamic Periorbital Lines
Background: Dynamic lines in the periorbital region are the first signs of aging. Dynamic lines show only when emoting, possibly becoming static lines present with worsening with age. Objective: This...
Read MoreThe Emerging Role of Metformin in Skin Cancer: Mechanistic and Clinical Insights
Background: Metformin, widely used for type 2 diabetes mellitus, has demonstrated antitumor effects through modulation of metabolic and immune pathways. This review explores its potential role in the ...
Read MoreIron Oxides in Tinted Sunscreen for Hyperpigmentation: A Product Analysis and Literature Review
Background: Hyperpigmentation disproportionately affects skin of color, often exacerbated by visible light (VL) exposure. Photoprotection in these populations remains underused due to the cosmetic inc...
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Features
Time is Tissue: A Representative Case Report Highlighting the Importance of Early Clinical Diagnosis of Necrotizing Fasciitis
Dermatologists' Practices and Perspectives on HPV, Surgical Plume, and Cancer Risk
Minimum Margins After Positive Mohs Surgery Stages Correlate With Histologic Facing Loss
Patients With Lichen Planopilaris Are at Increased Risk of Skin Cancer
Treatment or Trigger? The Use of Biologic Therapy for Alopecia Areata
Case Reports
Treatment of Confluent and Reticulated Papillomatosis Using Fixed-Dose Clindamycin phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel
Introduction: Confluent and reticulated papillomatosis (CARP) is a rare, non-systemic disease usually treated using oral antibiotics. Case Presentation: We present a 15-year-old male with CARP for wh...
Read MorePembrolizumab as an Off-Label Treatment of Facial Angiosarcoma: A Case Report
Summary of Case: We report an atypical case of cutaneous angiosarcoma presenting as unilateral nasal swelling in an elderly male. The lesion was unresponsive to topical and antibiotic therapy. Diagnos...
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Departments
FULL SUPPLEMENT: Mechanism Matters: IL-17 Receptor Blockade With Brodalumab and Its Role in Durable Psoriasis Clearance and Fast Onset of Action
Psoriasis is a chronic immune-mediated inflammatory disease driven by dysregulated interleukin-17 (IL-17) signaling across skin and musculoskeletal tissues. While upstream IL-23 inhibition and selecti...
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Supplements
INDIVIDUAL ARTICLE: Clinical and Real-World Implications of IL-17 Receptor Blockade in Plaque Psoriasis and Psoriatic Arthritis With Brodalumab
Brodalumab is a fully human monoclonal antibody targeting interleukin-17 receptor A (IL-17RA), providing a mechanistically distinct approach to inhibiting IL-17–mediated inflammation in plaque p...
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