Issue Archive
February 2007 | Volume 6 | Issue 2
Editorials
Hydroquinone and the FDA—The Debate?
Recently you may have received e-mails, telephone calls, letters or read articles stating that within the next few months, hydroquinone - our workhorse bleaching cream - will be banned in the US. ...
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Original Articles
Safety and Efficacy of Poly-L-Lactic Acid in HIV-Lipoatrophy and Lipoatrophy of Aging
Background: Poly-L-lactic acid (PLLA) is an injectable filler used for the treatment of facial fat loss secondary to HIV and aging. The US FDA approved PLLA for the treatment of HIV lipoatrophy in Au...
Read MorePanfacial Botulinum Toxin Improves Patient Retention
The injection of botulinum toxin (Botox®, Allergan, Irvine, CA) is the most common cosmetic procedure in the US. In the past 5 years, its use has climbed over 388%. In 2005, business development m...
Read MoreEfficacy of Microdermabrasion Preceding ALA Application in Reducing the Incubation Time of ALA in Laser PDT
Topical 5-aminolevulinic acid (ALA) and various light sources have been used to treat actinic keratoses and acne. Many of these regimens have required long incubation times due to the penetration qua...
Read MoreComparison of 5% 5-Fluorouracil Cream and 5% Imiquimod Cream in the Management of Actinic Keratoses on the Face and Scalp
It is timely to compare the efficacy and tolerability of 2 actinic keratosis (AK) therapies—5% 5-fluorouracil (5-FU) cream and imiquimod cream. Thirty-six patients with 4 or more AKs were rand...
Read MoreTruncal Acne Vulgaris: The Relative Roles of Topical and Systemic Antibiotic Therapy
Information is limited on the management of truncal acne vulgaris. Survey results suggest that most dermatologists commonly prescribe oral antibiotic therapy when treating acne involving the chest an...
Read MoreCost-Effectiveness of a Fixed Combination of Hydroquinone/Tretinoin/Fluocinolone Cream Compared with Hydroquinone Alone in the Treatment of Melasma
Background: A once-daily fixed combination of hydroquinone, tretinoin, and fluocinolone acetonide (Tri-luma) is a newly available treatment for melasma.
Objective: To assess cost-effectiven...
Read MoreColloidal Oatmeal: History, Chemistry and Clinical Properties
Oatmeal has been used for centuries as a soothing agent to relieve itch and irritation associated with various xerotic dermatoses. In 1945, a ready to use colloidal oatmeal, produced by finely grindin...
Read MoreSafety and Efficacy of Desonide Hydrogel 0.05% in Pediatric Subjects with Atopic Dermatitis
Low to mid potency corticosteroids remain a cornerstone of therapy for atopic dermatitis (AD). Since AD is most prevalent in the younger pediatric population and is chronic in nature, safety is of pa...
Read MorePharmacokinetics of Tacrolimus Following Topical Application of Tacrolimus Ointment in Adult and Pediatric Patients with Moderate to Severe Atopic Dermatitis
Objective: To characterize the pharmacokinetics of tacrolimus after topical application in adult and pediatric patients with moderate to severe atopic dermatitis from all clinical trials in which tac...
Read MoreEfficacy of Novel Skin Cream Containing Mixture of Human Growth Factors and Cytokines for Skin Rejuvenation
The crucial role of growth factors and cytokines in cutaneous wound healing is well described, but there has been little investigation into their use for skin rejuvenation. A novel skin cream contain...
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Features
Case Reports
Palliative Treatment of Fingernail Lichen Planus
Lichen planus of the nails is a destructive inflammatory onychodystrophy that is often difficult to treat. We report a case of treatment with combined topical therapy of tazarotene gel and clobetasol...
Read MoreOsteomyelitis Occurring during Infliximab Treatment of Severe Psoriasis
Tumor necrosis factor alpha (TNF-?) inhibitors, such as infliximab, decrease the body’s inflammatory response and thus the body’s reaction to infection. Given the immune-mediated proces...
Read MoreSkin Tightening by a New Unipolar and Bipolar Radiofrequency Device
Monopolar radiofrequency (RF) devices are well established treatment modalities for tightening facial skin. A 60-yearold woman presented with a desire to tighten the lax skin and improve the appearan...
Read MoreBexarotene and Interferon-α Combination Therapy in a Patient Affected by Relapsing Anaplastic Large Cell Lymphoma with Cutaneous Involvement
A 74-year-old man presented with relapsing systemic anaplastic large cell lymphoma (ALCL) with cutaneous involvement who had a third recurrence of cutaneous lesions associated with inguinal lymphonod...
Read MorePotential Foreign Body Emboli Associated with Botulinum Toxin A Injections
Although the injection of Botox Cosmetic for the treatment of dynamic rhytids is safe and effective, there is a potential risk for foreign body embolization. This case report documents the presence o...
Read MoreDermoscopy as a Tool for Rapid Diagnosis of Monilethrix
Monilethrix is a rare cause of hair loss. We present a case of a 44-year-old female, in whom dermoscopy enabled a rapid diagnosis of monilethrix. Dermoscopy images in this patient showed hair shafts ...
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