Issue Archive
February 2023 | Volume 22 | Issue 2
Original Articles
Efficacy and Safety of 1% Clascoterone Cream in Patients Aged > 12 Years With Acne Vulgaris
Background: Two randomized phase 3 studies evaluated efficacy and safety of 1% clascoterone cream, a topical androgen receptor inhibitor, in patients aged ≥9 years with moderate-to-severe facial ac...
Read MoreBurden, Control, and Treatment of Moderate to Severe Atopic Dermatitis in 2021: A United States Patient Survey Study
Background: Recent data on unmet needs in the treatment of moderate to severe atopic dermatitis (AD) in the US are not available.
Objective: To describe disease control, quality of life (QoL), a...
Read MoreMeeting Patient Expectations of Topical Psoriasis Treatment: Evidence Supporting the Use of Fixed-Combination Halobetasol/Tazarotene Lotion
Discordance between patient and clinician treatment goals and expectations can present a challenge to implementation of effective therapeutic plans. Because topical treatments are commonly used for pl...
Read MoreConcordance in Distinguishing Actinic Keratosis from Squamous Cell Carcinoma in Situ on Mohs Histological Frozen Sections
Background: Mohs surgeons routinely encounter squamous cell carcinoma at surgical margins and often base the decision to take another layer on the severity of atypia observed. Currently, no criteria e...
Read MoreA Qualitative Study on Dupilumab's Impact on Atopic Dermatitis Among Adolescent and Adult Patients
Background: Atopic dermatitis (AD) is the most common inflammatory skin disease and dupilumab is US Food and Drug Administration-approved in both adult and pediatric AD patients.
Objective: To q...
Read MoreEfficacy and Safety of Calcipotriene/Betamethasone Dipropionate Foam in the Treatment of Psoriasis in Skin of Color
Background: There is a paucity of data on usage of topical medications in patients with darker phototypes. This single-center, randomized, double-blinded, vehicle-controlled clinical study investigate...
Read MoreThe Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study
Background: Patients with atopic dermatitis (AD) need safe and effective topical treatments.
Objective: To assess safety and efficacy of roflumilast cream in patients with mild to moderate AD. <...
Read MoreAtopic Dermatitis Polypharmacy and Out-Of-Pocket Healthcare Expenses
Background: Atopic dermatitis (AD) out-of-pocket (OOP) expenses are substantial and impact household finances. Prescription polypharmacy and its association with OOP expenses in AD is poorly understoo...
Read MoreDevelopment and Validation of a Photonumeric Scale for Evaluation of Jawline Contour
Background: A naturally aged face is often characterized by a noticeable lack of jawline contour and decreased volume in the lower region. Several options are available to redefine the jawline. To obj...
Read MoreOnline Health Information for Acne Keloidalis Nuchae has a Difficult Level of Readability
Background: Acne keloidalis nuchae (AKN) is an inflammatory disorder primarily seen in individuals of color, characterized by acneiform and keloidal lesions on the occipital scalp/nuchal region. More ...
Read MoreMolluscum Contagiosum Virus Evasion of Immune Surveillance: A Review
Background: Molluscum contagiosum (MC) is an acute infection caused by the molluscum contagiosum virus (MCV) with a worldwide incidence of approximately 8,000 cases per 100,000 individuals annually. G...
Read MoreEfficacy and Safety of Water-Free Lipid Formulation System Containing Calcipotriol Against Psoriasis Vulgaris
Calcipotriol, a vitamin D analogue is widely used in the treatment of psoriasis. However, poor adherence to topical therapy has led to an ineffective use of the medication and built a barrier to the t...
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Features
Practical Approaches to the Diagnosis and Management of Sensitive Skin: A Scoping Review
Citation: McCormick ET, Desai S, Friedman A. Practical approaches to the diagnosis and management of sensitive skin: A scoping review. J Drugs Dermatol. 2023;22(2):223-225 doi:10.36849/JDD.2021.NVRN10...
Read MoreShining Light on PDT and Actinic Keratosis
Photodynamic therapy (PDT) is a non-invasive treatment modality involving photosensitizers that are activated by absorption of visible light to initially form the excited singlet state, followed by tr...
Read MoreAn Investigator-Initiated Trial of a Polymeric Emulsion of Halobetasol Propionate and Tazarotene in the Treatment of Palmoplantar Psoriasis
Copy: Palmoplantar psoriasis is a chronic, difficult-to-treat localized variant of psoriasis that affects the palms and soles, significantly affecting patient's quality of life.
Objective: To ev...
Read MorePigmented Basal Cell Carcinoma: An Argument for Sub-Classification
Basal cell carcinoma (BCC) has several subclassifications, including pigmented basal cell carcinoma. In our clinical experience, we have found that pigmented basal cell carcinoma itself has multiple s...
Read MoreDifferential RNA Transcriptome in Ustekinumab Responders vs Non-Responders
Despite numerous available psoriasis treatments, no "one size fits all" regimen provides complete disease control without side effects, logistical obstacles, and/or expense. Despite increasingly effic...
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Case Reports
Graham-Little-Piccardi-Lasseur Syndrome: A Case Report
Graham-Little Piccardi-Lasseur syndrome is a rare dermatosis that affects the hair follicles throughout the body and often presents with a progressive cicatricial alopecia of the scalp that is unrespo...
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Departments
FULL SUPPLEMENT: Pediatric Acne Patient Cases to Tailor Skincare as Monotherapy, Adjunctive, and Maintenance treatment
Adjunctive daily skin care throughout life promotes a healthy skin barrier and is beneficial in managing various inflammatory skin disorders in all populations. However, when choosing optimal treatmen...
Read MoreFULL SUPPLEMENT: A Review and Consensus on Promoting Skin Barrier Health Throughout Life Using Ceramide-Containing Skin Care
Adjunctive daily skin care throughout life promotes a healthy skin barrier and is beneficial in managing various inflammatory skin disorders in all populations. However, when choosing optimal treatmen...
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Supplements
Supplement Individual Article: Pediatric Acne Patients' Treatment Real-World Case Series Using Skincare as Monotherapy, Adjunctive, and Maintenance Treatment
Background: Pediatric acne is a common, complex, multifactorial inflammatory skin disease with various expressions in childhood that can be categorized by age, severity, and pubertal status. A pediatr...
Read MoreSupplement Individual Article: The Importance of a Healthy Skin Barrier From the Cradle to the Grave Using Ceramide-Containing Cleansers and Moisturizers: A Review and Consensus
Introduction: Inflammatory skin disorders compromise skin barrier health. Early and daily skincare use aims to maintain a life-long healthy skin barrier. Racial/ethnic and age variations in skin barri...
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