Issue Archive
December 2002 | Volume 1 | Issue 3
Original Articles
TNf-Alpha and Apoptosis: Implications for the Pathogenesis and Treatment of Psoriasis
TNF-alpha is a key cytokine in innate immune responses and is increased in psoriatic lesions. TNF-alpha has many effects, ranging from inflammation to apoptosis. These effects are reviewed to better ...
Read MoreThe Use of Tumescent Anesthetic Solution for Fat Transfer Donor and Recipient Sites
The use of tumescent anesthetic solution first described by Jeffrey Klein, M.D. in 1986 for liposuction has made fat transfer a technique well suited to a dermatologic surgeon's office1. Over the past...
Read MoreSurgical Complications
Dermatologic surgery is advancing at a very rapid pace. New procedures are being introduced and older techniques are being used for new applications every day, for both therapeutic and cosmetic purpos...
Read MoreThe History of Flaps
The History of Skin Grafts
Biologic Therapy for Psorasis- The First Wave: Infliximab, Etanercept, Efalizumab, and Alefacept
Over the last several years, a new generation of therapies for psoriasis has been in development. These biologic therapies target the activity of T lymphocytes and cytokines responsible for the infla...
Read MoreThe New Antihistamines-Desloratadine and Levocetirizine: A Review
Antihistamines are among the most commonly used medications by allergists and dermatologists worldwide. They are used to treat indications such as rhinitis, urticaria, seasonal allergies, and pruritus...
Read MoreThe Skin Cancer Foundation
Case Reports
A Young Boy with Symmetric Hyperkeratotic Plaques: Progressive Symmetric Erythrokeratoderma (PSEK)
In this report, a case is presented of a child, descendent from parents originating in the Virgin Islands, with symmetric and progressive hyperpigmented, hyperkeratotic plaques consistent with progre...
Read MoreIrbesartan- Associated Persistant Edema of the Eyelids, Face, and Neck
Irbesartan, an angiotensin II receptor antagonist(AIIRA), is an antihypertensive agent that inhibits the activity of angiotensin II by selectively binding to angiotensin II type 1 (AT1) receptors. The...
Read MoreManagement of Obstructive Airway Hemangiomans in the Neonate
Hemangiomas are benign neoplasms of vascular endothelium. They represent the most common pediatric tumor and are seen in 8-12% of Caucasian children by age 11. Hemangiomas have a female predilection, ...
Read MorePemphigus Foliaceus Presenting As Eruptive Seborrheic Keratosis and Responding to Oral Gold Treatment
Pemphigus Foliaceus (PF) is an antibody-mediated autoimmune disease. IgG directed against desmoglein-1 induces acantholysis in the superficial epidermis, leading to the classic presentation of cruste...
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