Issue Archive
April 2022 | Volume 21 | Issue 4
Editorials
An Analysis of Skin of Color Publications in the Journal of Drugs in Dermatology from 2018 to 2020
As the United States population becomes increasingly diverse, it is exceedingly important for dermatologists to be knowledgeable about treating patients with skin of color (SOC). The published li...
Read MoreA Retrospective Study of Idiopathic Granulomatous Mastitis Treatment and Outcomes
Granulomatous mastitis (GM) is a rare, poorly characterized inflammatory disease with a broad differential diagnosis that includes both benign and malignant conditions such as infectious mastitis, sar...
Read More
Original Articles
The Maintenance Effect of Calcipotriene 0.05% and Betamethasone Dipropionate 0.064% (Cal/BD) Aerosol Foam in Combination With Apremilast
Even in light of significant recent therapeutic advancements, many patients with psoriasis will use a combination of treatments at some point in the disease course. Despite the frequency with which co...
Read MoreOral Tranexamic Acid for the Treatment of Melasma: A Case Series and Novel Dosing Regimen
Melasma is a common disorder affecting millions of people around the world.1 It is a condition that can disrupt one’s self-esteem and overall quality of life.2 Melasma is characterized by hyperp...
Read MoreExpert Recommendations on the Use of Hyaluronic Acid Filler for Tear Trough Rejuvenation
Restylane® Lidocaine is one of the most widely used hyaluronic acid (HA) fillers to replace lost or displaced volume during tear trough correction. Patient goals for tear trough correction include...
Read MoreEvaluation of Cannabis and Cannabinoid Product Use, Knowledge, and Attitudes in the Eczema Community
Background: Data to date supports the potential for targeting the cutaneous endocannabinoid system to treat eczematous dermatoses. However, our understanding of patient knowledge and utilization of ca...
Read MoreLong-Term Treatment Patterns Among Patients With Psoriasis Treated With Ixekizumab or Adalimumab: A Real-World Study
Background: There is a paucity of long-term real-world evidence comparing the effectiveness of ixekizumab (IXE) and adalimumab (ADA). We compared real-world treatment patterns of IXE-treated and ADA-t...
Read MoreAnatomical Considerations for Injectable Fillers in the Face: How to Reduce Complications and Optimize Aesthetic Results
The popularity of minimally invasive injectable aesthetic treatments has grown exponentially with over thirteen million neurotoxin and dermal filler injections being performed in 2014. While aesthetic...
Read MoreLong-Term Skin Clearance With Brodalumab in Patients With Psoriasis and Inadequate Response to Prior Biologics
Background: Despite the emergence of multiple biologic drug options for psoriasis, unmet treatment needs remain. Biologic therapies can vary in their effectiveness and adverse events, and many patient...
Read MoreBotulinum Toxin in Hidradenitis Suppurativa: A Systematic Review
Background: Hidradenitis suppurativa disproportionately affects women, minorities, and skin of color. Botulinum toxin is a potential therapy; however, literature regarding its utility is sparse.
Read MoreAssessment of Circadian-based Antioxidants Plus a Comprehensive Brightener in Skin of Color Patients With Hyperpigmentation
Background: Hyperpigmentation disorders disproportionately affect individuals with skin of color. There is an unmet need for safe and effective topical treatments for this population.
Objective:...
Read MoreCurrent Issues in Global Onychomycosis Management
Introduction: Onychomycoses occur worldwide and are complex infections to treat. Diagnosis with standard culture methods has been problematic. Treatment historically used oral monotherapies. A selecti...
Read More
Features
Offering an Off-Label Therapeutic Algorithm for Lichen Planus
Lichen planus (LP) is a poorly characterized, chronic inflammatory dermatosis notable for violaceous to brown/ black polygonal pruritic papules and plaques, often with lacey scale, and reticular white...
Read MoreDemographics of Dietary Supplement Use for Skin: An Analysis of NHANES Cross-Sectional Data
Dietary supplement use is common, with reported use by over half of US adults. This cross-sectional study utilized 2015–2016 National Health and Nutrition Examination Survey data. A total of 997...
Read MoreSafety and Efficacy of Intense Pulsed Light With Radiofrequency in United States Hidradenitis Suppurativa Patients
Copy: The combination of intense pulsed light and radiofrequency has been described in German populations to be a noninvasive therapy option for patients with hidradenitis suppurativa, demonstrating s...
Read MorePustular and Erythrodermic Psoriasis in Patients Treated With Oral Glucocorticoids: A Survey of United States Dermatologists
Dermatology dogma has cautioned against the use of orally administered glucocorticoids (OAG) in the treatment of psoriasis, largely due to concerns of life-threatening generalized pustular psoriasis (...
Read More
Case Reports
Improvement of Unilateral Breast Hypoplasia With Oral Spironolactone in a Patient With Becker Nevus Syndrome
Becker nevus (BN) is a benign cutaneous smooth muscle hamartoma that presents with a hyperpigmented patch or plaque with or without hypertrichosis.1 BN may be associated with ipsilateral breast hypopl...
Read MoreA Case of Late-Onset Alopecia Areata
Alopecia areata (AA) is a condition characterized by nonscarring hair loss. Cases of alopecia areata are most commonly seen in patients under age 30 and are frequently idiopathic. In this report, we d...
Read MoreDeep Sweet Syndrome Secondary to Pegfilgrastim
Sweet syndrome, or acute febrile neutrophilic dermatosis, is a skin condition consisting of erythematous papules and plaques in association with fever, neutrophilia, and a neutrophilic infiltrate that...
Read More
Supplements
FULL SUPPLEMENT: SCIENTIFIC AND CLINICAL INSIGHTS INTO THE USE OF MINERALIZING THERMAL WATER-CONTAINING SERUM FOR REDUCING FACIAL EXPOSOME IMPACT
This review explores scientific and clinical insights into the exposome impact on facial skin aging and the potential benefits of topical mineralizing volcanic water use....
Read MoreSUPPLEMENT ARTICLE: Scientific and Clinical Insights into the Facial Application of Mineralizing Volcanic Water
Background: The term "exposome" describes the totality of exposures an individual is subjected to from conception to death. Both internal and external exposome factors affect skin health. External exp...
Read MoreFULL SUPPLEMENT: DERMATOLOGIC DRUG DESIGN GOES RETRO
This supplement aims to provide a brief overview of retrometabolic drug design and a summary of the impact of the retrometabolic approach in other specialties. It highlights the use of retrometabolica...
Read MoreINTRODUCTION: Retrometabolic Drug Delivery in Dermatology
A fundamental aspect of dermatologic diagnosis and treatment is our visibly ready access to the site of skin disease. Just as we can often render a diagnosis based on visual assessment of a lesion or ...
Read More
