Issue Archive
March 2022 | Volume 21 | Issue 3
Editorials
Acne Information on Instagram: Quality of Content and the Role of Dermatologists on Social Media
While it is evident that many patients turn to social media for information about skin care, the quality and content of available information are not well characterized. In this study, we investigated...
Read MoreUpdates In Therapeutics for Lichen Planus Pigmentosus
Lichen planus pigmentosus (LPP) is a rare variant of lichen planus presenting most commonly in middle-aged patients of color and characterized by the insidious onset of violaceous, brown, or grayish p...
Read MoreUstekinumab in the Management of Hidradenitis Suppurativa: A Retrospective Study
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by the formation of recurrent abscesses in apocrine-bearing areas. In advanced stages, chronic inflammation leads to...
Read MoreAssessing Dermatology Provider Perceptions and Attitudes About the Unique Needs of Older Adult Patients
Geriatric dermatology is an emerging field of dermatology, focused on the unique needs of older adults with dermatological diagnoses. Previous research identified important principles to consider in o...
Read MoreA Randomized Trial of Oral Tranexamic Acid With Fluocinolone-Based Triple Cream Versus Fluocinolone Based Triple Cream Alone for the Treatment of Melasma
Oral tranexamic acid (TXA) is a relatively new treatment option for melasma. It is thought to reduce hyperpigmentation through inhibition of the plasminogen/plasmin pathway with resulting decreases in...
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Original Articles
Extrafacial Merkel Cell Carcinoma Presenting as a Cyst
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin tumor that presents as an erythematous or violaceous nodule in elderly white males with an extensive history of sun exposure. Here...
Read MoreDermoscopy and Reflectance Confocal Microscopy in Actinic Keratosis, Intraepithelial Carcinoma, and Invasive Squamous Cell Carcinoma
Background: Patients with multiple actinic keratosis (AK), have pre-neosplastic abnormalities, constituting the sites of new tumors, this region is called the cancerization field. Due to the risk of m...
Read MoreGetting to the Core of Contemporary Therapies for Post-Inflammatory Hyperpigmentation
Post-inflammatory hyperpigmentation (PIH) is a typical complication of inflammatory dermatoses that more frequently and severely affects people with darker skin. External insults to the skin, such as ...
Read MoreA Prospective, Multicenter Trial on the Efficacy and Safety of Poly-L-Lactic Acid for the Treatment of Contour Deformities of the Buttock Regions
Background: There is a significant emphasis on minimally invasive whole-body rejuvenation throughout the world. Recently, gluteal aesthetics have become an increasingly common patient concern. Althoug...
Read MorePooled Analysis Demonstrating Superior Patient- Reported Psoriasis Treatment Outcomes for Calcipotriene/ Betamethasone Dipropionate Cream Versus Suspension/Gel
Background: Calcipotriene and betamethasone dipropionate (CAL/BDP) cream is a novel treatment of plaque psoriasis based on PAD™ Technology (PAD-cream) designed to improve patient reported treatm...
Read MoreThe Impact of Racial Differences on Treatment Strategies in Hidradenitis Suppurativa: A Retrospective Review
Background: Hidradenitis suppurativa (HS) is a chronic disease that causes inflammatory lesions typically found in the axillary, inguinal, and perineal regions that can result in permanent scarring, f...
Read MoreImplications of Serum Anti-Ceramide Antibodies and Interleukin 4 on Nerve Damage and Physical Impairments Among Leprotic Patients: A Case-Controlled Study
Background: Leprosy is a chronic granulomatous disease affecting skin and nerves with a range of clinical and immunological responses. Objectives: The study aimed to identify levels of IL-4 and antibo...
Read MoreAnalysis of Reddit Reveals Dupilumab Questions Among Atopic Dermatitis Patients
Background: Atopic dermatitis patients are turning to social media to seek guidance and source medical information. Reddit, the seventh most visited website in the US, contains the popular “ecze...
Read MoreAdjunctive Use of Calcipotriene 0.005%/Betamethasone Dipropionate 0.064% Foam in Patients With Psoriasis Treated With Ixekizumab
Objective: To examine the effectiveness and safety of adjunctive treatment with calcipotriene 0.005%/betamethasone dipropionate 0.064% (Cal/BD) foam in adult patients with chronic plaque psoriasis who...
Read MoreIn Vitro Rheology Predicts Improved Spreadability of Tazarotene 0.045% Lotion Versus Trifarotene 0.005% Cream
Background: Intrinsic properties of vehicles used to deliver topical therapies can profoundly impact drug penetration, efficacy, patient acceptance, and treatment adherence. Therefore, advancements in...
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Case Reports
Successful Treatment of Cheilitis Granulomatosa With Certolizumab and Ustekinumab
Cheilitis granulomatosa (CG) is a subtype of orofacial granulomatosis that results in facial and oral swelling in the absence of non-caseating granulomatous systemic diseases such as Crohn’s and...
Read MoremTOR Inhibitor-Induced Transient Acantholytic Dermatitis
A 61-year-old Caucasian male with a medical history of metastatic carcinoid presented to dermatology with a new onset severely pruritic “breakouts” on the arms, neck, and chest. Approximat...
Read MorePustular Psoriasis Appearing Induced by Dupilumab Therapy in a Patient With Atopic Dermatitis
Dupilumab inhibits T-helper 2 (Th2)-driven inflammation cascade by blocking interleukin-4 (IL-4) and IL-13 signaling, which has been recognized to play a crucial role in the pathogenesis of atopic der...
Read MoreRefractory Dissecting Cellulitis of the Scalp Treated With Risankizumab
Perifolliculitis capitis abscedens et suffodiens or dissecting cellulitis (DC) is a rare and chronic disease with a predilection for the occipital, vertex, and parietal scalp. DC is characterized by m...
Read MorePlatelet Rich Plasma for the Treatment of Scarring Alopecia Due to Discoid Lupus Erythematosus
Platelet-rich plasma (PRP) is an autologous concentration of plasma from a patient’s blood containing platelets up to 7 times higher than normal plasma. Originally indicated to improve connectiv...
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