Issue Archive
May 2021 | Volume 20 | Issue 5
Editorials
Topical Metronidazole After Discontinuation of Oral Metronidazole for Continuing Treatment of Lichen Planus
Characterization and Clinical Significance of Non-Scarring Alopecia in Systemic Lupus Erythematosus
Non-scarring alopecia is now part of the Lupus International Collaborating Clinics classification criteria 2012 (SLICC’12). We set out to better characterize the timing and distribution of lupus...
Read MoreUsing 31-Gene Expression Profile in Melanoma Risk Prognosis
Management of Traction Alopecia: Our Experience and a Brief Review of Current Literature Recommendations
Traction alopecia is a common hair loss condition related to hair shaft trauma and sustained pulling leading to hair follicle loosening and inflammation. Although often categorized as nonscarring, inc...
Read MoreAssessing the Risk of Apremilast Use for Psoriasis During the COVID-19 Pandemic
Assessing the Risk of Apremilast Use for Psoriasis During the COVID-19 Pandemic.
Apremilast, a phosphodiesterase-4 (PDE-4) inhibitor, is an oral small molecule inhibitor approved for ...
Read MoreHome Sweat Specimen Collection as Part of Gravimetric Sweat Production Assessment for Axillary Hyperhidrosis Studies
Remdesivir Use in COVID-19 Patients: Cutaneous Adverse Effect or Disease Manifestation?
Remdesivir Use in COVID-19 Patients: Cutaneous Adverse Effect or Disease Manifestation?...
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Original Articles
Influence of Rheological Properties and Needle Size on Extrusion Forces of Hyaluronic Acid Based Soft Tissue Fillers
Background: To date no precise data are available for extrusion forces related to the G-prime and G-double-prime of fillers in combination with different 27G and 30G needles. Therefore, the objective ...
Read MoreProspective Clinical Trial Evaluating the Long-Term Safety and Efficacy of Calcium Hydroxylapatite for Chest Rejuvenation
Background: Calcium hydroxylapatite (CaHA) is indicated for correcting moderate-to-severe facial wrinkles and folds. Hyperdilute CaHA is increasingly being used for stimulating neocollagenesis to impr...
Read MoreManagement of Primary Focal Hyperhidrosis: An Algorithmic Approach
Hyperhidrosis (HH) is defined as perspiration beyond the level required to maintain temperature regulation. HH affects nearly 4.8% of the population in the United States. It can have a great impact on...
Read MoreRandomized, Double-Blind, Placebo-Controlled Study of Poly-L-Lactic acid for Treatment of Cellulite in the Lower Extremities
Background: Poly-l-lactic acid (PLLA) is an injectable volumizer with biostimulatory properties used for volumetric structural rejuvenation in patients with facial fat volume loss but has increasingly...
Read MoreTreatment Update of Port-Wine Stain: A Narrative Review
Background: Port-wine stain (PWS) is a congenital vascular malformation affecting 0.3–0.5% of normal population. These characteristic lesions arise due to the interplay of vascular, neural, and ...
Read MoreBovine Colostrum, Telomeres, and Skin Aging
Background: Applied topically, growth factors, cytokines, and other components in bovine colostrum are known to affect collagen biosynthesis, thus offering promise as a therapeutic modality in wound h...
Read MoreBasal Cell Carcinoma Gene Mutations Differ Between Asian, Hispanic, and Caucasian Patients: A Pilot Study
Background: Basal cell carcinoma (BCC) is the most common malignancy worldwide. While most BCCs are treated surgically, advanced BCCs are often treated with gene-targeted therapies. While there has be...
Read MoreComparative Evaluation of Efficacy and Safety of Tacrolimus and Dinoprostone Following Dermabrasion in Stable Vitiligo
Background: Dinoprostone (DNP), a prostaglandin E2 (PGE2) analogue, has been found to cause repigmenation in vitiliginous lesions. Combined medical and surgical therapy might be more useful for succes...
Read MoreComparative Study of Intralesional Vitamin D3 Injection and Candida Albicans Antigen in Treating Plantar Warts
Background: Warts, or verrucae, are mucosal human papilloma virus (HPV) infections that are very challenging to treat.
Objective: To compare the safety and efficacy of intralesional injection of...
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Features
Full Face and Neck Treatment With OnabotulinumtoxinA in Patients With Facial Palsy
Two Cases of Recalcitrant Dyshidrotic Eczema Treated With Dupilumab
Dyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a chronic, relapsing palmoplantar dermatosis characterized by intensely pruritic and frequently painful deep...
Read MoreBilateral Contiguous Scrotal Extramammary Paget's Disease Treated With Mohs Micrographic Surgery and CK7 Immunohistochemical Staining
Extramammary Paget’s Disease (EMPD) is a rare malignancy that commonly presents on apocrine-rich skin as a unilateral scaly patch or plaque that often grows slowly and asymmetrically. There is g...
Read MoreThe Effect on BSA of Proactive Management versus Reactive Management of Psoriasis With Fixed-Dose Cal/BD Foam in the PSO-LONG Study
Reduction of psoriasis body surface area (BSA) is associated with improved patient quality of life. Post-hoc analyses of the PSO-LONG study compared impact on BSA of proactive management versus reacti...
Read MoreAnatomical Definition of the Target Structures of a Jet-Based Tissue Penetration
Case Reports
A Case of Cutaneous Blastic Plasmacytoid Dendritic Cell Neoplasm Treated With a Bcl-2 Inhibitor
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive primary cutaneous lymphoma characterized by transformed plasmacytoid dendritic cells that overexpress interleukin-3 recept...
Read MoreVismodegib as Eye-Sparing Neoadjuvant Treatment for Locally Advanced Periocular Basal Cell Carcinoma
Locally-advanced periocular basal cell carcinoma (BCC) pose many therapeutic challenges due to the need to preserve functionality and cosmesis of the orbit and periocular area. Surgical excision and s...
Read MoreNovel Treatment of In-Transit Metastatic Melanoma With Shave Excision, Electrodesiccation and Curettage, and Topical Imiquimod 5% Cream
In-transit metastatic melanoma is classified as a regional intralymphatic metastasis of melanoma. Currently, there is no standardized regimen used to treat in-transit metastatic melanoma, and therapy ...
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Supplements
FULL SUPPLEMENT: Status Update: Isotretinoin
ARTICLE: Why Absorica LD?
ARTICLE: Advances in Oral Isotretinoin Therapy
Since its approval in 1982, oral isotretinoin has revolutionized acne therapy. However, oral isotretinoin use has long been associated with challenges of variable bioavailability and food dependence. ...
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