Issue Archive
April 2006 | Volume 5 | Issue 4
Original Articles
Metronidazole in the Treatment of Rosacea: Do Formulation, Dosing, and Concentration Matter?
Background: Topical metronidazole is commonly used in the management of rosacea. No consensus on the optimal formulation, concentration, or dosing regimen exists.
Purpose: To assess the rela...
Read MoreSun Protection Strength of a Hydroquinone 4%/Retinol 0.3% Preparation Containing Sunscreens
Background: Dyschromias are common and significantly impact patients’ quality of life. Formulas containing hydroquinone 4% are effective in these conditions. Since exposure to ultraviolet radiat...
Read MoreShort-Term Safety Assessment of Clobetasol Propionate 0.05% Shampoo: Hypothalamic–Pituitary–Adrenal Axis Suppression, Atrophogenicity, and Ocular Safety in Subjects with Scalp Psoriasis
Clobetasol propionate is known to be a very effective treatment for psoriasis; however, its use is limited by potent corticosteroid class related side effects such as hypothalamic-pituitary-adrenal (...
Read MoreTopical Tacrolimus for the Treatment of Psoriasis on the Face, Genitalia, Intertriginous Areas and Corporal Plaques
Tacrolimus is an immunosuppressive drug that has proved effective in the treatment of psoriasis when administered systemically. Topically, it seems only useful in thin psoriasis plaques located on th...
Read MoreAlefacept in the Treatment of Psoriatic Nail Disease: A Proof of Concept Study
Nail psoriasis can be debilitating and as therapeutic options are limited, it can be notoriously difficult to treat. As there are many new medications currently undergoing clinical trials in psoriasi...
Read MoreThe Utility of Benzoyl Peroxide in Hydrophase Base (Brevoxyl®) in the Treatment of Acne Vulgaris
Available for more than 5 decades, benzoyl peroxide has been a “workhorse†of acne therapy. The benefits of this agent include reduction in Propionibacterium acnes (P. acnes) with decreas...
Read MorePhotodynamic Therapy Induces Less Pain in Patients Treated with Methyl Aminolevulinate Compared to Aminolevulinate Acid
Background: Plaque psoriasis affects about 2% of the US population. A new and unique spray formulation of clobetasol propionate (CP) 0.05% was developed to provide advantages over the currently avail...
Read MoreAn Intra-Individual Randomized Safety and Efficacy Comparison of Clobetasol Propionate 0.05% Spray and its Vehicle in the Treatment of Plaque Psoriasis
Background: Plaque psoriasis affects about 2% of the US population. A new and unique spray formulation of clobetasol propionate (CP) 0.05% was developed to provide advantages over the currently avail...
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Features
Case Reports
Uncontrollable Prurigo Nodularis Effectively Treated by Roxithromycin and Tranilast
Treatment of prurigo nodularis (PN) is often very difficult even with strong corticosteroid dressing and other available means. Macrolide roxithromycin (RXM) is used in consideration of its immunosup...
Read MoreRecurrent Injection Site Reactions from Interferon Beta 1-b
Recombinant human interferon beta-1b is an immune-modulatory drug used for a variety of conditions including multiple sclerosis (MS). Skin reactions to therapeutic use of injectable interferon beta-1...
Read MoreEpidermal Growth Factor Receptor (EGFR) Inhibitor Associated Skin Eruption
EGFR Inhibitors are used to treat Non-Small-Cell Lung Cancer (NSCLC) and colorectal cancer (CRC). A common side effect of EGFR Inhibitors is a follicular/pustular skin eruption. We report a case of g...
Read MoreNon-Sarcoidal, Non-Tuberculoid Granuloma in Common Variable Immunodeficiency
Sarcoidal (non-caseating) or tuberculoid granulomas are cutaneous manifestations of common variable immunodeficiency (CVID). In this case report, we describe a patient with CVID but with non-sarcoida...
Read MoreDapsone in the Treatment of Persistent Erythema Multiforme
Erythema multiforme (EM) is usually an acute and self-limited inflammatory reaction of the skin and mucous membranes. Attacks may be sporadic or recurrent, and generally last for 1 to 3 weeks. Rarely...
Read MoreNicolau Syndrome: A Report of 2 Cases
Nicolau syndrome or embolia cutis medicamentosa is a very rare, but well recognized complication of intramuscular injections which clinically presents with extensive necrosis of the injected skin are...
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