Issue Archive
July 2005 | Volume 4 | Issue 4
Original Articles
A Double-Blinded, Placebo-Controlled Study of Botox® for the Treatment of Subjects with Chin Rhytids
Background: Botox has been used primarily for treating rhytids of the upper face. Its use in the lower part of the face has been reported by several authors but there is a relative scarcity of inform...
Read MoreBrown Recluse Spider Envenomation: Dermatologic Application of Hyperbaric Oxygen Therapy
Envenomation from the brown recluse (Loxosceles recluse) spider commonly proceed on one of three clinical pathways. The majority of bites (90%) result in nothing more than a local reaction. They are ...
Read MoreA Review of the Chemopreventive and Chemotherapeutic Effects of Topical and Oral Retinoids for both Cutaneous and Internal Neoplasms
Retinoids, a group of compounds encompassing Vitamin A and its analogs, have been shown to inhibit tumor growth in laboratory studies. Based on these findings, a number of clinical trials have been c...
Read MoreComparison of Intense Pulsed Light to 595-nm Long-Pulsed Pulsed Dye Laser for Treatment of
Background: The short-pulsed pulsed dye laser (PDL) has been previously reported to improve the appearance of hypertrophic scars. Prolonged purpura following treatment led to the development of the n...
Read MoreTopical Anesthetics for Cosmetic and Laser Dermatology
Many effective and simple topical anesthetic products are available today and commonly used in medical and non-medical settings. The increased use of topical anesthetics, especially by non-physicians...
Read MoreNew Histopathological Classification of Actinic Keratosis (Incipient Intraepidermal Squamous Cell Carcinoma)
Actinic keratoses are common, sun-induced lesions that have historically been regarded as “premalignant.†Evidence supports their inclusion along a continuum with squamous cell carcinoma....
Read MoreBlood Pressure Levels Decrease during Mohs Micrographic Surgery
Background: A common practice is not to operate on patients with elevated blood pressure (BP) levels to avoid cardiovascular and cerebrovascular complications. We therefore designed a study to evalua...
Read MoreTopical Metronidazole Combination Therapy in the Clinical Management of Rosacea
Metronidazole was the first topical agent approved by the US Food and Drug Administration for the treatment of rosacea. Several controlled studies have confirmed the efficacy and safety of topical me...
Read MoreCiclopirox Topical Solution, 8% Combined with Oral Terbinafine to Treat Onychomycosis: A Randomized, Evaluator-Blinded Study
This randomized, evaluator-blind, 3-arm parallel, comparator controlled, multicenter pilot study evaluated the safety and efficacy of ciclopirox nail lacquer topical solution, 8% in combination with ...
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Features
Case Reports
Cutaneous Small Vessel Vasculitis due to Famciclovir Therapy
Cutaneous hypersensitivity vasculitis is often idiopathic, but may be the result of therapeutic drugs. It is important to be aware of previously unreported drugs that may be associated with this comp...
Read MoreMitozantrone-Induced Onycholysis Associated with Subungual Abscesses, Paronychia, and Pyogenic Granuloma
Chemotherapeutic agents may induce a wide variety of adverse mucocutaneous effects, including nail changes. We present a case of atypical onycholysis, associated with subungual abscess formation, par...
Read MoreSuicidal Ideation in the Dermatology Clinic
Many dermatology patients have significant psychiatric comorbidities, including depression and suicidal ideation. In light of the isotretinoin controversy, the relevance of this subject has never bee...
Read MoreAcne Fulminans in Marfan Syndrome
We report on a 12-year-old boy suffering from acne fulminans in combination with Marfan syndrome. The trigger for acne induction seemed to be a testosterone therapy. The particular therapeutic proble...
Read MoreVerapamil-Induced Subacute Cutaneous Lupus Erythematosus
Calcium-channel blockers (CCB), including verapamil, nifedipine, and diltiazem, are one of the most widely prescribed class of drugs in the treatment of cardiovascular disease. In the last several ye...
Read MoreTreatment of Nevirapine-Associated DRESS Syndrome with Intravenous Immune Globulin (IVIG)
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an adverse drug reaction most commonly associated with aromatic antiepileptic agents. It is characterized by the triad of skin er...
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