Issue Archive
August 2017 | Volume 16 | Issue 8
Editorials
A Major Win for the Treatment of Nail Psoriasis
Despite mounting evidence that biologics provide the fastest and most efficacious for nail psoriasis, it remains challenging for patients to get access to these medications, often requiring concomitan...
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Original Articles
The Static Physician’s Global Assessment of Genitalia: A Clinical Outcome Measure for the Severity of Genital Psoriasis
Introduction: Genital psoriasis is a common but frequently overlooked manifestation of psoriasis with a considerable impact on patients’ quality of life. Currently no validated clinic...
Read MoreMethods for Imputing Missing Efficacy Data in Clinical Trials of Biologic Psoriasis Therapies: Implications for Interpretations of Trial Results
BACKGROUND: An issue in long-term clinical trials of biologics in psoriasis is how to handle missing efficacy data. This methodological challenge may not be understood by clinicians, yet can have a si...
Read MoreA Comparative Study to Evaluate Epidermal Barrier Integrity of Psoriasis Patients Treated With Calcipotriene/Betamethasone Topical Suspension Versus Betamethasone Dipropionate 0.05% Lotion
BACKGROUND: Topical corticosteroids are known to impair the epidermal barrier, even after short-term use, whereas topical vitamin D analogues can have a reparative effect. Combination products using c...
Read MoreTopical Desoximetasone 0.25% Spray and Its Vehicle Have Little Potential for Irritation or Sensitization
BACKGROUND: Topical corticosteroids are the most common dermatologic medications and are available in numerous different vehicles. Adherence is limited by traditional vehicles because they are messy a...
Read MoreTreatment of Inverse/Intertriginous Psoriasis: Updated Guidelines from the Medical Board of the National Psoriasis Foundation
Inverse or intertriginous psoriasis commonly involves skin fold areas including the axillae, perianal skin, intergluteal cleft, inframammary, genital/inguinal, abdominal, and retroauricular folds. Aft...
Read MoreInternational Dermatology Outcome Measures (IDEOM) Group 2016 New York Meeting: Meeting Summary and Data from the Psoriasis Working Group
The International Dermatology Outcome Measures (IDEOM) Group was established to develop validated and standardized patient-centered outcome measures in dermatology that meet the needs of stakeholders ...
Read MoreAdalimumab in Chronic Plaque Psoriasis: A Clinical Guide
Psoriasis is a common, inflammatory disease that manifests itself as lesions on the skin, which greatly impacts the physical and psychological wellbeing of those affected. The current goal of treatmen...
Read MoreEfficacy and Safety of Apremilast in Patients With Moderate Plaque Psoriasis With Lower BSA: Week 16 Results from the UNVEIL Study
INTRODUCTION: Many options are available for patients with moderate to severe plaque psoriasis. Patients with moderate disease, however, are often undertreated and do not achieve satisfactory clearanc...
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Case Reports
Submammary Granular Parakeratosis Treated With Mastopexy
Granular parakeratosis, originally named axillary granular parakeratosis, is an uncommon disease with an unclear etiology. It is thought to result from defective processing of profillagrin to fillagri...
Read MoreTwenty-Nail Transverse Melanonychia Induced by Hydroxyurea: Case Report and Review of the Literature
Twenty-nail transverse melanonychia from hydroxyurea is a rare phenomenon, only reported four times previously. Here we describe a 51-year-old female who presented with 20-nail transverse melanonychia...
Read MoreTemporal Association of Herpes Zoster Eruption Post-Aminolevulinic Acid Hydrochloride Photodynamic Therapy for Actinic Keratoses
Herpes zoster is a common and painful disease caused by the reactivation of the varicella-zoster virus with a higher incidence and severity associated with increasing age as well as compromised immune...
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Supplements
Clinical Review: Secukinumab in Psoriatic Diseases
Psoriasis Is a Chronic Disease: Long Term Efficacy and Safety of New Biologics Is Important...
Read MorePsoriasis Is a Chronic Disease: Long Term Efficacy and Safety of New Biologics Is Important
Increased understanding of psoriasis has led to a shift in treatments from non-specific immunosuppressants to targeted biologics. Studies in psoriasis have demonstrated minimal risk and substantial be...
Read MoreSecukinumab: Long-term Safety and Efficacy in Psoriasis
Secukinumab: A Review of Safety and Efficacy in Psoriatic Arthritis
Effect of a Blueberry-Derived Antioxidant Matrix on Infrared -A Induced Gene Expression in Human Dermal Fibroblasts
There is compelling evidence that Infrared A (IRA) from natural sunlight contributes to photoaging of human skin by inducing the expression of matrix metalloproteinase-1 (MMP-1) expression in human de...
Read MoreEffect of a Blueberry-Derived Antioxidant Matrix on Infrared-A Induced Gene Expression in Human Dermal Fibroblasts
There is compelling evidence that Infrared A (IRA) from natural sunlight contributes to photoaging of human skin by inducing the expression of matrix metalloproteinase-1 (MMP-1) expression in human de...
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