Issue Archive
May 2004 | Volume 3 | Issue 3
Original Articles
New Insights into Imiquimod's Mechanisims of Action
Imiquimod, an immune response modifier with potent antiviral and antitumor properties, has been reported to be effective in the treatment of various cutaneous neoplasms. Besides stimulating the produ...
Read MoreRosacea: Where Are We Now?
Advances continue to be made in the classification and treatment of rosacea, a chronic dermatologic syndrome. A new empiric classification system identifies 4 rosacea subtypes (erythematotelangiectat...
Read MoreIntralesional Immunotherapy for Warts Using a Combination of Skin Test Antigens
Warts are a common dermatologic problem. There are many treatments available. Intralesional injection of a skin test antigen has been shown to be efficacious at eradicating all warts when only a part...
Read MoreLong-Term Fat Preservation
The injection of autologous free fat obtained by suction-assisted lipectomy for the correction of soft tissue defects is a common procedure in plastic surgery. However, unpredictable partial absorpti...
Read MoreEtanercept for the Treatment of Psoriasis: Combination Therapy with other Modalities
Etanercept is a self-administered medication that has FDA approval for the treatment of rheumatoid arthritis, juvenile rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Etanercep...
Read MoreOff-label Uses and Side Effects of Infliximab
Infliximab was first approved by the FDA in 1998 as a treatment of moderately-to-severely active Crohn’s disease in patients who have an inadequate response to conventional therapies, and fist...
Read MoreAntiandrogen Oligonucleotides: Active Principles in Hair-and Skin-Derived Culute Cells
Most drugs used for treatment of androgen-related dermatological disorders are not completely satisfactory in terms of clinical efficacy and potential secondary effects. There is, therefore, a need f...
Read MoreThe IFRA: Working Towards the Continually-Improved Safety of Fragrance Ingedients and the Importance of a Partnership with the Dermatological Community
The relationship between the fragrance industry and the dermatological community in the past has not always been perceived as one of partnership. IFRA, the International Fragrance Association, has st...
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Case Reports
Follicular Mycosis Fungoides: Successful Treatment with Oral Bexarotene
Follicular mycosis fungoides, a subtype of cutaneous T-cell lymphoma, is often difficult to treat. We present a case of a female with follicular mycosis fungoides who showed an excellent response to ...
Read MoreSerum Sickness due to Infliximab in a Patient with Psoriasis
Infliximab is a chimeric, murine-human, monoclonal antibody against tumor necrosis alpha which has shown great efficacy in the treatment of psoriasis. Serum sickness, which is an immune complex media...
Read MoreSolitary Mastocytoma Successfully Treated with a Moderate Potency Topical Steriod
We report a case of solitary mastocytoma in a child which was successfully treated with a topical steroid of moderate potency. The patient was an 18-month-old girl who presented with localized oval s...
Read MoreLupus Erythematosus and Lichen Planus Overlap Symdrome
A case of lupus erythematosus (LE) and lichen planus (LP) overlap syndrome in a 71-year-old woman is presented. This disease displays characteristics of both LE and LP. The clinical, histologic, and ...
Read MoreCounter-Regulatory Balance: Atopic Dermatitis in Patients Undergoing Infliximab Infuson Therapy
Atopic dermatitis has been characterized as an autoimmune or auto-allergic phenomenon in which environmental allergens resembling human proteins activate auto-reactive T-cells to release pro-inflamma...
Read MorePalmar Erythema due to Topiramate
Topiramate is an anti-convulsant often used off-label for the treatment of several conditions, including obesity and schizophrenia. This case report describes palmar erythema as a side effect in a pa...
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