Issue Archive
January 2004 | Volume 3 | Issue 1
Original Articles
Redefining Clinical Response in Psoriasis: Targeting the Pathological Basis of Disease
Psoriasis is a chronic inflammatory disease of the skin that can have a major effect on patient quality of life. Conventional psoriasis treatments, often identified empirically, fail to meet the clin...
Read MoreTopical Treatment of Actinic Keratosis with Fluorouracil: Is Irritation Associated with Efficacy?
Actinic keratoses (AKs) are common dysplastic epidermal lesions that share clinical, histologic, and molecular features with squamous cell carcinoma. Therapeutic options include destructive modalitie...
Read MoreImpact of Efalizumab on Psoriasis-Specific Patient-Reported Outcomes
The objective of this study was to document the disease burden associated with moderate to severe plaque psoriasis, and assess the impact of efalizumab psoriasis treatment in improving patient-report...
Read MorePhotorejuvenation with Intense Pulsed Light: Results of a Multi-Center Study
This multi-center study evaluating the role of Intense Pulsed Light (IPL) in the non-ablative rejuvenation of Type I and Type II photoaged skin study was conducted in order to evaluate the clinical e...
Read MoreOnychomycosis: Classification and Diagnosis
Onychomycosis is a common infection of the nail predominantly caused by anthropophilic dermatophytes, and to a lesser extent by yeasts (Candida species) and non-dermatophyte molds. The treatment of o...
Read MorePicaridin: A New Insect Repellent
Picaridin is a new insect repellent that is comparable in effect and less irritating than diethyl toluamide (deet). Its activity and effects are reviewed in this article....
Read MoreDermatologic Look- or Sound-Alike Medications
Medication errors contribute substantially to patient injury and death, with 25% of these errors attributed to drug names that look or sound alike. This article was written to heighten the awareness ...
Read MoreThe Nuances of Dealing with Cosmetic Patients
Case Reports
Imiquimod as a Possible Treatment for Keratoacanthoma
Imiquimod is an immune-response modifier that has the potential to be useful in many dermatological indications (Table 1). To date, the approved use is for condyloma acuminata; approval for use in tr...
Read MoreLocalized Heat Induced Urticaria: Report of a Case
Localized heat induced urticaria is a rare clinical entity. Other physical urticarial subtypes include cholinergic, solar, cold, aquagenic, vibratory, and dermatographic. It is characterized by a wel...
Read MoreGeneralized Pustular Psoriasis Following Withdrawal of Efalizumab
Efalizumab is one of the new biologic therapies targeting T-lymphocyte activity for the treatment of chronic plaque psoriasis. Common adverse effects include headaches, nonspecific infection, nausea,...
Read MoreCutaneous Vasculitis Secondary to Ramipril
A 61-year-old patient who had been treated with lisinopril in the past without any problems was commenced on ramipril for left ventricular dysfunction. He developed a painful symmetrical purpuric eru...
Read MoreVenous Thrombosis Occurring After Initiation of Thalidomide for the Treatment of Cicatricial Pemphigoid
Thalidomide is increasingly being used for the treatment of a variety of dermatologic conditions. Some of the risks associated with thalidomide use, however, are still being uncovered. Increased inci...
Read MorePrimary Cutaneous B-cell Lymphoma in a 74-Year-Old Caucasian Male
Primary cutaneous B-cell lymphoma is an uncommon neoplasm with classification schemes that may be confusing, but with clinical presentations that are relatively consistent. Clinical exam and history ...
Read MoreGenetic Testing for Inherited Predisposition to Melanoma: Has the Time Come?
