Original Articles

• Botulinum Toxin B; The New Option in Cosmetic Injection

  Botulinum toxin, one of the nature's most toxic substances, is the unlikely source of one of cosmetic dermatology's most popular new injectable treatment options. The article describes the physiologic...
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• Pulse Therapy With 5-FU In Eradicating Actinic Keratosis With Less Than Recommended Dosage

  Pulse therapy has been used for many years, but rarely in a clinical setting. This article describes a clinical study designed to determine the efficacy of pulse therapy with 5-FU for patients with mu...
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• Are Boosters or Supplementation of Anti-fingal Drugs of Any Use For Treating Onychomycosis?

  It is widely accepted that there is a finite failure rate when treating onychomycosis; a case report from the author serves as an example of multiple failures following treatments of varying duration ...
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• The Role of Cyclooxygenase-2 in the Pathogenesis of Skin Cancer

  Prostaglandin synthesis occurs via the coordinate action of a phospholipase that liberates arachidonic acid from membrane phospholipids and a cyclooxygenase (COX) that converts the free arachidonic ac...
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• Drug Samples: Friend or Foe?

  The common practice of drug manufacturers in providing 'free' samples to physicians has influenced the business of medicine in several ways. This article analyzes some of the pros and cons of drug sam...
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• Sclerotherapeutic Agents Used For Treatment of Spider and Varicose Veins:Update 2002

  Sclerotherapy for varicose and spider veins is a commonly performed procedure in dermatology and dermatologic surgery; before the advent of botulinum toxin injection for wrinkles, it was the most comm...
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• Allopurinol Hypersensitivity Syndrome

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• Generalized Pustules in a Healthy Woman

  A healthy 47-year-old woman developed diffuse pustules and edema of the skin after exposure to diltiazem and cephalexin. Bacterial, fungal and viral cultures were sterile suggesting a noninfectious et...
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• Baboon Syndrome caused By Salasate

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• A Case of Scurvy in an Autistic Boy

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• Reversal Reaction to Hansen's Disease

  A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented. His clinical features included erythem...
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• Mixed Cryoglobulinemia Secondary to Interferon Therapy for Hepatitis C

  Mixed cryoglobulinemia is a systemic vasculitis associated with hepatitis C infection. We present a case of mixed cryoglobulinemia induced by interferon-a therapy for hepatitis C infection and review ...
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