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Female pattern hair loss (FPHL) results from a combination of hormones, aging, and genetics, and is the most common type of alopecia in women. Topical minoxidil remains the only United States Food and Drug Administration (FDA)-approved treatment for this condition, although numerous other therapies have demonstrated efficacy in recent years.¹

To develop reliable diagnostic methods and more effective hair loss treatments, researchers are exploring technologies like machine learning (ML), a subset of artificial intelligence (AI). ML analyzes data and makes decisions using preprogrammed algorithms. While still in its infancy, ML may help clinicians curate unique, personalized treatment approaches. Current research indicates promise of ML in diagnosing specific types of hair loss, personalizing therapeutic interventions, and objectively evaluating treatment response.

Microneedling (MN) is a minimally invasive procedure which permits the transdermal delivery of drugs, preferably 5% minoxidil or more recently clascoterone solution and exosomes rather than others (growth factors, PRP, dutasteride, Botox), confirming its effective and safe therapeutic value as innovative refinement for hair restoration, particularly in mild-moderate androgenetic alopecia (AGA) management.

Traction alopecia is a common hair loss condition related to hair shaft trauma and sustained pulling leading to hair follicle loosening and inflammation. Although often categorized as nonscarring, increasing evidence indicate that late-stage traction alopecia (TA) can cause permanent hair loss and scarring from chronic folliculitis and sustained hair tension. TA is often seen in women of African descent, although cases have been reported in African men, Hispanic women, Japanese women, Sikh men, and ballet dancers. Early effective treatment is needed to prevent progression and potential scarring; therefore, a review and summary of published literature for best practices is necessary and valuable. 

Alopecia Areata: The Clinician and Patient Voice

The review synthesizes clinician and patient survey data to describe the lived burden of alopecia areata, the condition course, and current care gaps. It highlights the profound psychosocial impact and quality of life impairments that patients experience, including anxiety and depression, and summarizes clinician observations about diagnostic challenges and therapeutic limitations.

Article Highlight: Efficacy of Topical Finasteride 0.25% With Minoxidil 5% Versus Topical Minoxidil 5% Alone in Treatment of Male Pattern Androgenic Alopecia

This article from November’s JDD study reveals a potential game-changer in the fight against Androgenetic Alopecia (male pattern baldness). Researchers compared two popular treatments for hair regrowth, and one combination therapy delivered significantly superior results. Could this new approach offer a more effective solution for millions of men?

AI-Powered Personalization for Hair Loss: A Promising Alternative?

With up to 50% of women and 80% of men experiencing hair loss, many turn to generic over-the-counter solutions—often with disappointing results. Could AI-driven customization be the answer?

Beyond Minoxidil: Is It Time to Rethink Female Hair Loss Treatment?

More than half of postmenopausal women, and a significant percentage of younger, healthy women, struggle with visible hair loss, often starting as early as their reproductive years. Whether it’s androgenetic alopecia, telogen effluvium, or scarring forms like lichen planopilaris and central centrifugal cicatricial alopecia, the psychological toll is undeniable. Yet, despite its prevalence, FDA-approved treatment options remain frustratingly limited.

Emerging Topical Approaches in the Management of Female Pattern Hair Loss

Alopecia can be categorized as cicatricial and non-cicatricial, with female androgenetic alopecia (AGA) and female pattern hair loss (FPHL) included in the latter category.

Efficacy of a Dual-Serum Cosmetic System in Women With Female Pattern Hair Loss

Hair loss is a widespread condition with a potentially severe psychological burden, especially among women. The chance of suffering from female alopecia increases with menopause, and topical treatments beyond minoxidil are scarce. Over the past several years, new combinations of natural ingredients and patented mixtures have shown promising results to improve hair shedding, thus helping recover self-esteem and confidence.