November 1, 2019

Don’t Go Zero to TEN: Identifying Gaps that Lead to Drug Re-exposure in Toxic Epidermal Necrolysis

Drs. Helena Pasieka and Adam Friedman

We’ve all been there – that dreaded middle of the night page/call from the ER. Three simple words that send us spinning: “Rule out TEN.” Have no fear though, because the skin sloughing savoir is here. Inpatient dermatology service director Dr. Helena Pasieka joins us to discuss her recent research that elucidates opportunities to prevent offending agent re-exposure (aka first time shame on you, second time shame on us) in patients with a history of SJS/TEN. Simple steps can be taken to improve communication and prevention. Even more importantly, Dr. Pasieka walks us through her tried and true approach to that r/o call, key findings to guide your decision making, and what to when. Listening to this podcast may save someone’s life…

JDD Article Referenced in this Podcast:
Recommendations for Prevention of Drug Re-Exposure in Toxic Epidermal Necrolysis
Kathleen F. O’Brien MS, Karl M. Saardi MD, Laura S. Johnson MD, Jeffrey W. Shupp MD, Nemanja Rodic MD PhD, and Helena B. Pasieka MD MS
J Drugs Dermatol. 2019;18(10):1049-1052.

A CME exam is available for this podcast.

Learning Objectives:
Upon completion of this enduring activity, participants should be able to:
Discuss common reasons for SJS patient re-exposure to offending agents and
Review an orderly approach to diagnosing and managing SJS/TEN spectrum.

Adam Friedman, MD – No relevant disclosures.
Helena Pasieka, MD – No relevant disclosures.

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