Successful Treatment of Disseminated Granuloma Annulare With Adalimumab

February 2009 | Volume 8 | Issue 2 | Case Reports | 169 | Copyright © February 2009

David Rosmarin MD, Anne LaRaia MD, Scott Schlauder MD, Alice B. Gottlieb MD PhD

A 61-year-old-female with a 4-year history of disseminated granuloma annulare was successfully treated with the antitumor necro- sis factor (TNF)-alpha antibody, adalimumab. The patient had failed high potency topical glucocorticoids, hydroxychloroquine, and narrow-band ultraviolet light (UV)-B phototherapy. Anti-TNF-alpha therapy may be a therapeutic option in patients with disseminated granuloma annulare poorly controlled with conventional medications.