INTRODUCTIONPost-inflammatory hyperpigmentation (PIH) is a pigmentary disorder in which the skin develops reactive hyper melanosis due to different exogenous and endogenous factors.1 PIH is induced by an excess of melanin…
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INTRODUCTIONIn addition to providing temporary soft tissue augmentation, non-invasive treatment of volume loss is one of the most common aesthetic treatments performed worldwide. Hyaluronic acid (HA) fillers are the treatment…
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INTRODUCTIONAtrusted and well-known topical treatment of plaque psoriasis is the fixed-dose combination of calcipotriene (CAL; Vitamin D analogue) and betamethasone dipropionate (BDP; corticosteroid). There is a solid scientific rationale for…
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INTRODUCTIONHidradenitis Suppurativa (HS) is a chronic disease that causes inflammatory lesions typically found in the axillary, inguinal, and perineal regions that can result in permanent scarring, fibrosis, and sinus tract…
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INTRODUCTIONLeprosy is a chronic granulomatous disease caused by mycobacterium leprae (M. Leprae) with a specific predilection to cutaneous and neural tissue. Immunologic and inflammatory changes result in a wide range…
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INTRODUCTIONCheilitis granulomatosa (CG) is a subtype of orofacial granulomatosis that results in facial and oral swelling in the absence of non-caseating granulomatous systemic diseases such as Crohn’s and sarcoidosis.1 With…
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INTRODUCTIONCommon among adolescents and adults, acne vulgaris accounts for a significant portion of dermatology appointments.1 While there are a variety of safe, effective, and evidence-based treatments available, there are also…
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INTRODUCTIONSocial media is an emerging piece of the chronic disease management puzzle. Given the speed, accessibility, and convenience of the Internet, patients are increasingly consulting the web to source medical…
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CASE REPORTA 61-year-old Caucasian male with a medical history of metastatic carcinoid presented to dermatology with a new onset severely pruritic “breakouts” on the arms, neck, and chest. Approximately ten…
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INTRODUCTIONDupilumab inhibits T-helper 2 (Th2)-driven inflammation cascade by blocking interleukin-4 (IL-4) and IL-13 signaling, which has been recognized to play a crucial role in the pathogenesis of atopic dermatitis (AD)…
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INTRODUCTIONPsoriasis is a chronic, immune-mediated inflammatory disease affecting approximately 3% of the US population.1 The pathogenesis of psoriasis involves keratinocyte hyperproliferation, which manifests as itchy, scaly erythematous plaques on the…
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INTRODUCTIONThe vehicle used to deliver a topical therapy composes the majority of a drug’s formulation, and vehicle optimization thus represents an opportunity to maximize drug penetration, efficacy, patient acceptance, and…
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