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Feb 24
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The Frequency of Non-Scarring Alopecia in Autoimmune Connective Tissue Diseases

By Chuck Lin No Comments
INTRODUCTIONAlopecia is a common troubling symptom in dermatology. It can be divided into various categories and is usually classified clinically and histopathologically into scarring and non-scarring alopecia.1 It can also…
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Feb 21
Love0

Effect of Recombinant Human Hyaluronidase on Conventional Hyaluronic Acid Fillers: An In Vitro Analysis

By Chuck Lin No Comments
INTRODUCTIONSoft tissue augmentation is an increasingly popular aesthetic medical procedure. Hyaluronic acid (HA) fillers are commonly utilized for soft tissue augmentation.1 An advantage of HA fillers includes easy reversibility with…
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Feb 21
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Comparative Efficacy of Intralesional Steroid Injections vs Cryotherapy for the Treatment of Alopecia Areata

By Chuck Lin No Comments
INTRODUCTIONAlopecia areata (AA) is a distinct pathological condition characterized by non-scarring hair loss due to autoimmune processes and inflammation.1 It can present as patchy alopecia, alopecia totalis (AT), or alopecia…
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Feb 20
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Disparities in Alopecia Areata and Vitiligo FDA-Approved Therapies in Medicaid Formularies

By Chuck Lin No Comments
INTRODUCTIONVitiligo and alopecia areata (AA) are two common, autoimmune dermatologic diseases that significantly impact quality of life.1,2 Oral and topical JAK inhibitors are innovative, emerging treatments. The FDA has approved…
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Feb 19
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Keeping Cool: An Updated Review on Cold-Induced Dermatoses and Cold-Associated Injury

By Chuck Lin No Comments
INTRODUCTIONThe skin's protective role as the first defense against environmental exposures makes it susceptible to climatic stressors. Low temperatures, in particular, compromise the skin's barrier through the activity of transient…
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Feb 19
Love0

Neoadjuvant Sonidegib for the Management of Locally Advanced Basal Cell Carcinoma: A Case Report

By Chuck Lin No Comments
INTRODUCTIONNeoadjuvant Hedgehog Pathway Inhibitor (HPI) therapy, encompassing sonidegib, and vismodegib has emerged as a promising strategy in the management of locally advanced basal cell carcinoma (laBCC).1 This approach is currently…
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Feb 12
Love0

Differentiating and Managing Cutaneous Lupus Erythematosus-Associated Alopecia and Patchy Alopecia Areata: Therapeutic Insights From Case Studies

By Chuck Lin No Comments
INTRODUCTIONCutaneous lupus erythematosus (CLE), a group of autoimmune skin diseases characterized by skin eruptions including, but not limited to photosensitivity, malar rash, discoid lupus erythematosus (DLE), and subacute cutaneous lupus…
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Feb 03
Love0

The Potential Risk of Povidone-Iodine in Sperm Quality: A Case Report

By Chuck Lin No Comments
INTRODUCTIONCompound PVP-I liniment is a widely used over-the-counter dermatology drug indicated in the treatment of fungal or bacterial infections of the skin or nails, in which each milliliter contained 30…
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Feb 01
Love0

Insights Into Demographics, Comorbidities, and Risk Factors in Keloids and Hypertrophic Scars: A Retrospective Study

By Chuck Lin No Comments
INTRODUCTION Hypertrophic scars, those that are raised and confined to the wound margin, and keloidal scars, those that extend beyond the wound margin, are manifestations of abnormal wound healing.1 In…
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Jan 31
Love0

A Multi-Component Reaction Peptide Augmenting the Anti-Aging Benefits of Non-Ablative Laser Procedure

By Chuck Lin No Comments
INTRODUCTIONLaser resurfacing has been the gold standard for the rejuvenation of photodamaged skin over the past four decades.1-4 Ablative laser procedures can efficiently address signs of aging by vaporizing the…
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Jan 31
Love0

INDIVIDUAL ARTICLE: Ruxolitinib 1.5% Cream and the “Boxed Warning Paradox”: Reappraisal of Safety Through the Lens of Pharmacokinetics

By Chuck Lin No Comments
INTRODUCTIONJanus kinase (JAK) proteins are key, evolutionarily conserved mediators of external-to-internal cellular signaling, activated when external cytokines bind to their respective transmembrane receptors, triggering phosphorylation of JAK proteins, then STAT…
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Jan 31
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INDIVIDUAL ARTICLE: Appraisal of Ruxolitinib 1.5% Cream as a First-Line Topical Therapeutic Agent for Adolescents and Adults With Mild-to-Moderate Atopic Dermatitis

By Chuck Lin No Comments
INTRODUCTIONThe topical therapeutic landscape of atopic dermatitis (AD) has entered the "golden age" of drug development. Until now, the landscape was comprised of 3 major mechanistic classes: (1) corticosteroids, calcineurin…
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