CASE REPORTA 61-year-old Caucasian male with a medical history of metastatic carcinoid presented to dermatology with a new onset severely pruritic “breakouts” on the arms, neck, and chest. Approximately ten…
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INTRODUCTIONDupilumab inhibits T-helper 2 (Th2)-driven inflammation cascade by blocking interleukin-4 (IL-4) and IL-13 signaling, which has been recognized to play a crucial role in the pathogenesis of atopic dermatitis (AD)…
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INTRODUCTIONPsoriasis is a chronic, immune-mediated inflammatory disease affecting approximately 3% of the US population.1 The pathogenesis of psoriasis involves keratinocyte hyperproliferation, which manifests as itchy, scaly erythematous plaques on the…
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INTRODUCTIONThe vehicle used to deliver a topical therapy composes the majority of a drug’s formulation, and vehicle optimization thus represents an opportunity to maximize drug penetration, efficacy, patient acceptance, and…
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INTRODUCTIONLichen planus pigmentosus (LPP) is a rare variant of lichen planus presenting most commonly in middle-aged patients of color and characterized by the insidious onset of violaceous, brown, or grayish…
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INTRODUCTIONDissecting cellulitis (DC) is a progressive disease that warrants prompt and adequate diagnosis and treatment to prevent scarring and irreversible hair loss. Since data on treatment options for DC are…
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INTRODUCTIONHidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by the formation of recurrent abscesses in apocrine-bearing areas.1 In advanced stages, chronic inflammation leads to sinus tract formation and…
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INTRODUCTIONGeriatric dermatology is an emerging field of dermatology, focused on the unique needs of older adults with dermatological diagnoses. Previous research identified important principles to consider in older adults with…
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INTRODUCTIONPlatelet-rich plasma (PRP) is an autologous concentration of plasma from a patient’s blood containing platelets up to 7 times higher than normal plasma.1 Originally indicated to improve connective tissue regeneration…
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INTRODUCTIONOral tranexamic acid (TXA) is a relatively new treatment option for melasma. It is thought to reduce hyperpigmentation through inhibition of the plasminogen/plasmin pathway with resulting decreases in epidermal melanocyte…
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INTRODUCTIONVarious types of artificial intelligence (AI), including machine learning and its subfield, deep neural network, have been successful and increasingly implemented in the healthcare field during the past decade due…
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INTRODUCTIONMohs micrographic surgery (MMS) is increasingly utilized for treatment of skin cancer, however the technique used is markedly different than other surgical modalities.1,2 Explaining MMS to patients is difficult, and…
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