INTRODUCTIONInhibitors of the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway have arrived in dermatology with a big bang: three oral JAK inhibitors were approved by the Food…
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INTRODUCTIONAcne vulgaris is an inflammatory skin disease characterized by proliferation of bacteria, hyperkeratinization, and increased sebum production, prevalent in approximately 85% of adolescents and young adults aged 12 to 24…
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INTRODUCTIONCancer is a condition where an aberrant mimicry of embryogenesis occurs to create an autonomous entity in one part of the body that has the potential to spread to other…
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INTRODUCTIONSurgical intervention is seen as the gold standard in the treatment of Squamous cell carcinoma. Yet, in cases of recurrence, repeated surgical procedures may unwittingly foment the rise of reactive…
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INTRODUCTIONLinear IgA bullous disease (LABD) is a rare, acquired, autoimmune skin condition that is associated with urticarial plaques and subepidermal blistering and mainly affects young children and older adults.1 In…
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INTRODUCTIONVitiligo is a complex multifactorial disorder of depigmentation affecting 0.5 to 2% of the world's population without specific gender or racial prevalence.1 Though no treatments are FDA approved to repigment…
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INTRODUCTIONHidradenitis suppurativa (HS) is an inflammatory skin disease characterized by deep suppurative nodules and abscesses generally in areas containing apocrine glands. Previously thought to be caused by dysregulated processes affecting…
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INTRODUCTIONTofacitinib is a Janus kinase (JAK) 1-3 inhibitor first U.S. Food and Drug Administration (FDA) approved in 2012 for rheumatoid arthritis, with subsequent approval for psoriatic arthritis, ulcerative colitis, polyarticular…
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INTRODUCTIONBacteriophages, also known as phages, are viruses that were first described in 1915 by an English bacteriologist, Frederick Twort, when he published findings of an agent capable of destroying bacteria.1,2…
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INTRODUCTION Androgenetic alopecia (AGA) is the most common cause of hair loss, affects up to 70% of men and 40% of women over the course of their lifetime, and is…
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INTRODUCTIONAccording to the Global Cancer Observatory (International Agency for Research on Cancer ), the United States has the 5th highest cancer incidence per 100,000 population.1 The US National Program of…
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INTRODUCTIONAcne vulgaris (acne) is ranked by the Global Burden of Disease Project as the eighth most prevalent disease worldwide.1,2 Globally, the prevalence of acne is estimated at 9.4%, affecting 650…
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