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Apr 25
Love0

The Prevalence of Sunscreen Use: A Cohort Study

By Chuck Lin No Comments
Skin cancer is the most commonly diagnosed malignancy worldwide and continues to grow as a major public health concern. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), collectively referred…
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Apr 25
Love0

Ultraviolet B-Rays Induced Gene Alterations and DNA Repair Enzymes in Skin Tissue

By Chuck Lin No Comments
INTRODUCTIONDeoxynucleic acid (DNA) damage caused by ultraviolet (UV) light in humans has been well documented and described in the literature.1-5 However, the ability to detect DNA damage is typically only…
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Apr 25
Love0

A Review of Antithrombotic Agents in Dermatologic Surgery and Context for a Practical Approach, With Cardiology and Pharmacologic Input

By Chuck Lin No Comments
INTRODUCTIONDermatologic surgeons are performing an increasing number of surgeries to diagnose and treat cutaneous malignancies.1 Bleeding complications occur in approximately 0.1% to 4% of patients, with patients taking antithrombotic therapies…
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Apr 24
Love0

Assessing the Efficacy of Imiquimod Use in Patients With Persistent Locally Advanced Melanoma In Situ

By Chuck Lin No Comments
INTRODUCTIONMelanoma in situ (MMIS) is a prominent stage of melanoma, defined as noninvasive and confined to the epidermis. In the United States, there are approximately 207,000 new melanoma cases each…
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Apr 21
Love0

The Role of Skin Substitutes in Dermatologic Surgery: A Practical Review

By Chuck Lin No Comments
INTRODUCTIONWound care is a major aspect of dermatology. Whether wounds are seen in the postoperative or consultation setting or when managing chronic non-healing ulcerations, dermatologists and dermatologic surgeons should be…
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Apr 21
Love0

Dilute Intralesional 5-Fluorouracil for the Treatment of Squamous Cell Carcinomas and Keratoacanthomas: A Case Series

By Chuck Lin No Comments
INTRODUCTIONIntralesional 5-fluorouracil (5-FU) is a promising, yet sparsely studied alternative to surgical treatment for nonmelanoma skin cancer (NMSC).1 While intralesional 5-FU is not a Food and Drug Administration (FDA)-approved treatment…
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Apr 19
Love0

Non-Invasive Diagnosis of Sun Damaged Skin: Actinic Keratosis Vs Squamous Cell Carcinoma

By Chuck Lin No Comments
INTRODUCTIONActinic keratosis (AK) is considered to be a pre-cancerous lesion arising in response to chronic exposure to sunlight. While there are many presentations of AK, it is often characterized as…
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Apr 19
Love0

Utility of Gene Expression Profiling in Skin Cancer: A Comprehensive Review

By Chuck Lin No Comments
INTRODUCTIONCurrent Staging Methods and the Need for Gene Expression Profiling Skin cancer is the most prevalent malignancy in the United States.1 By current estimations, 1 in 5 Americans will develop…
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Apr 17
Love0

Anti-Tumor Necrosis Factor Alpha Therapeutic Drug Monitoring in Inflammatory Disease: A Systematic Review

By Chuck Lin No Comments
INTRODUCTIONEmerging therapies for many chronic inflammatory dermatologic diseases, including hidradenitis suppurativa (HS), use monoclonal antibodies (biologics) to target inflammation. Currently, best evidence for HS treatment exists for adalimumab, an injectable…
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Apr 13
Love0

Comparing Histological Preparation and Tumor Debulking Techniques in Mohs Micrographic Surgery: A Cross-Sectional Survey

By Chuck Lin No Comments
INTRODUCTIONSingle-section Mohs (SSM) allows for the most accurate histological representation of tissue’s in vivo architecture during Mohs Micrographic Surgery (MMS).1 Traditional debulking involves pre-surgical curettage and taking tumor layers using…
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Apr 01
Love0

Self-Reported Long-Term Side Effects of Isotretinoin: A Case Series

By Chuck Lin No Comments
INTRODUCTION Isotretinoin is considered the gold standard treatment for severe nodulocystic acne, though it has been the subject of controversy in the media for concerns related to adverse psychiatric effects.…
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Mar 29
Love0

Do Atopic Dermatitis Patient-Reported Outcomes Correlate With Validated Investigator Global Assessment? Insights From TARGET-AD Registry

By Chuck Lin No Comments
INTRODUCTIONAtopic dermatitis (AD) is a chronic, immune-mediated skin condition characterized by erythematous, pruritic lesions frequently first diagnosed in childhood.1 Its pathophysiology is complex and multifactorial, with clinical presentation and severity…
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