Skin cancer is the most commonly diagnosed malignancy worldwide and continues to grow as a major public health concern. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), collectively referred…
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INTRODUCTIONDeoxynucleic acid (DNA) damage caused by ultraviolet (UV) light in humans has been well documented and described in the literature.1-5 However, the ability to detect DNA damage is typically only…
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INTRODUCTIONDermatologic surgeons are performing an increasing number of surgeries to diagnose and treat cutaneous malignancies.1 Bleeding complications occur in approximately 0.1% to 4% of patients, with patients taking antithrombotic therapies…
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INTRODUCTIONMelanoma in situ (MMIS) is a prominent stage of melanoma, defined as noninvasive and confined to the epidermis. In the United States, there are approximately 207,000 new melanoma cases each…
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INTRODUCTIONWound care is a major aspect of dermatology. Whether wounds are seen in the postoperative or consultation setting or when managing chronic non-healing ulcerations, dermatologists and dermatologic surgeons should be…
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INTRODUCTIONIntralesional 5-fluorouracil (5-FU) is a promising, yet sparsely studied alternative to surgical treatment for nonmelanoma skin cancer (NMSC).1 While intralesional 5-FU is not a Food and Drug Administration (FDA)-approved treatment…
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INTRODUCTIONActinic keratosis (AK) is considered to be a pre-cancerous lesion arising in response to chronic exposure to sunlight. While there are many presentations of AK, it is often characterized as…
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INTRODUCTIONCurrent Staging Methods and the Need for Gene Expression Profiling Skin cancer is the most prevalent malignancy in the United States.1 By current estimations, 1 in 5 Americans will develop…
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INTRODUCTIONEmerging therapies for many chronic inflammatory dermatologic diseases, including hidradenitis suppurativa (HS), use monoclonal antibodies (biologics) to target inflammation. Currently, best evidence for HS treatment exists for adalimumab, an injectable…
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INTRODUCTIONSingle-section Mohs (SSM) allows for the most accurate histological representation of tissue’s in vivo architecture during Mohs Micrographic Surgery (MMS).1 Traditional debulking involves pre-surgical curettage and taking tumor layers using…
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INTRODUCTION Isotretinoin is considered the gold standard treatment for severe nodulocystic acne, though it has been the subject of controversy in the media for concerns related to adverse psychiatric effects.…
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INTRODUCTIONAtopic dermatitis (AD) is a chronic, immune-mediated skin condition characterized by erythematous, pruritic lesions frequently first diagnosed in childhood.1 Its pathophysiology is complex and multifactorial, with clinical presentation and severity…
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