INTRODUCTIONGranuloma annulare (GA) is a benign, inflammatory granulomatous skin disease with an estimated annualized prevalence of ~0.06% in the United States.1 The most common subtypes are localized and generalized GA…
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INTRODUCTIONDermatoporosis describes thin, aged, and excessively fragile skin resulting from loss of the skin's protective mechanical function.1 Other signs and symptoms include skin atrophy, purpura, pseudoscars, skin lacerations, and dissecting…
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INTRODUCTIONAtopic dermatitis (AD) is the most common chronic inflammatory skin disorder globally, with an estimated prevalence of 31.6 million people in the United States (US) alone.1,2 AD characteristically presents with…
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INTRODUCTIONAtopic dermatitis (AD) is a multifactorial disease associated with both genetic risk factors and environmental stimuli. AD is also associated with dysbiosis, notably increased colonization by Staphylococcus aureus, and the…
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INTRODUCTION Hair loss is a prevalent issue affecting both men and women, often leading to considerable psychological distress. The causes of hair loss are multifaceted, encompassing medical conditions, medications, emotional…
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INTRODUCTIONAcetyl hexapeptide-8, marketed as Argireline® (Lipotec, Barcelona, Spain), is a six-amino-acid biomimetic of botulinum toxin promoted as a wrinkle-reducing compound. It entered the market in 2001 and has grown in…
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INTRODUCTIONHidradenitis Suppurativa (HS) is a notoriously difficult-to-treat inflammatory skin condition characterized by the presence of deep, painful nodules, abscesses, tracts, and fibrotic scars, often occurring in intertriginous and apocrine gland-rich…
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INTRODUCTIONGlucagon-like peptide-1 (GLP-1) agonists are used to treat type 2 diabetes mellitus (T2DM) and have recently gained approval and popularity for treating obesity and weight loss. With the recent increase…
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INTRODUCTION Socioeconomic development is associated with cancer's prevalence and distribution. According to the GLOBOCAN Estimates of Incidence and Mortality Worldwide, the estimated incidence rate (ASR) for males and females in…
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INTRODUCTIONAtopic dermatitis (AD) is a common, chronic inflammatory skin disease for which cutaneous dysbiosis is a core component of disease pathophysiology.1,2 AD-associated dysbiotic changes in the skin microbiome composition include…
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INTRODUCTIONImmune checkpoints are inhibitory pathways within the immune system that maintain self-tolerance and regulate the duration and strength of immune responses.1 Tumors can exploit this mechanism to evade immune surveillance…
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INTRODUCTION Acne is the most common cutaneous disease worldwide and the most frequent disorder to present to the dermatology practice. Although efficacious treatments exist, clinicians continue to search for better…
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