INTRODUCTIONIntralesional 5-fluorouracil (5-FU) is a promising, yet sparsely studied alternative to surgical treatment for nonmelanoma skin cancer (NMSC).1 While intralesional 5-FU is not a Food and Drug Administration (FDA)-approved treatment…
Read More
INTRODUCTIONActinic keratosis (AK) is considered to be a pre-cancerous lesion arising in response to chronic exposure to sunlight. While there are many presentations of AK, it is often characterized as…
Read More
INTRODUCTIONCurrent Staging Methods and the Need for Gene Expression Profiling Skin cancer is the most prevalent malignancy in the United States.1 By current estimations, 1 in 5 Americans will develop…
Read More
INTRODUCTIONEmerging therapies for many chronic inflammatory dermatologic diseases, including hidradenitis suppurativa (HS), use monoclonal antibodies (biologics) to target inflammation. Currently, best evidence for HS treatment exists for adalimumab, an injectable…
Read More
INTRODUCTIONSingle-section Mohs (SSM) allows for the most accurate histological representation of tissue’s in vivo architecture during Mohs Micrographic Surgery (MMS).1 Traditional debulking involves pre-surgical curettage and taking tumor layers using…
Read More
INTRODUCTION Isotretinoin is considered the gold standard treatment for severe nodulocystic acne, though it has been the subject of controversy in the media for concerns related to adverse psychiatric effects.…
Read More
INTRODUCTIONAtopic dermatitis (AD) is a chronic, immune-mediated skin condition characterized by erythematous, pruritic lesions frequently first diagnosed in childhood.1 Its pathophysiology is complex and multifactorial, with clinical presentation and severity…
Read More
IntroductionOften dismissed as a cosmetic concern, vitiligo is anything but given its pathophysiology and tremendous impact on quality of life (QoL). Simply put- vitiligo is a medical disease,1 exhibiting an…
Read More
INTRODUCTIONAs with much of dermatology, most research on wound healing has been based on afflictions in light skin, resulting in a dearth of evidence-based protocols on the management of wound…
Read More
INTRODUCTIONThe Burden of Melasma Melasma is a clinically diagnosed benign acquired pigmentary disorder that typically presents as symmetric, reticulated hypermelanosis with irregular borders. It appears on the centrofacial region (ie,…
Read More
INTRODUCTIONDiabetes mellitus (DM) type 1 (DM-1) and type 2 (DM-2) is a worldwide public health problem affecting over 460 million people globally in 2019; and estimated to rise to 578…
Read More
IntroductionThe immune response comprises a complex cascade of reactions that balances effector and regulatory functions.1 While the effector’s arm includes cellular and molecular components responsible for preventing cellular infections and…
Read More
