INTRODUCTIONEmerging therapies for many chronic inflammatory dermatologic diseases, including hidradenitis suppurativa (HS), use monoclonal antibodies (biologics) to target inflammation. Currently, best evidence for HS treatment exists for adalimumab, an injectable…
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INTRODUCTIONSingle-section Mohs (SSM) allows for the most accurate histological representation of tissue’s in vivo architecture during Mohs Micrographic Surgery (MMS).1 Traditional debulking involves pre-surgical curettage and taking tumor layers using…
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INTRODUCTION Isotretinoin is considered the gold standard treatment for severe nodulocystic acne, though it has been the subject of controversy in the media for concerns related to adverse psychiatric effects.…
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INTRODUCTIONAtopic dermatitis (AD) is a chronic, immune-mediated skin condition characterized by erythematous, pruritic lesions frequently first diagnosed in childhood.1 Its pathophysiology is complex and multifactorial, with clinical presentation and severity…
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IntroductionOften dismissed as a cosmetic concern, vitiligo is anything but given its pathophysiology and tremendous impact on quality of life (QoL). Simply put- vitiligo is a medical disease,1 exhibiting an…
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INTRODUCTIONAs with much of dermatology, most research on wound healing has been based on afflictions in light skin, resulting in a dearth of evidence-based protocols on the management of wound…
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INTRODUCTIONThe Burden of Melasma Melasma is a clinically diagnosed benign acquired pigmentary disorder that typically presents as symmetric, reticulated hypermelanosis with irregular borders. It appears on the centrofacial region (ie,…
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INTRODUCTIONDiabetes mellitus (DM) type 1 (DM-1) and type 2 (DM-2) is a worldwide public health problem affecting over 460 million people globally in 2019; and estimated to rise to 578…
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IntroductionThe immune response comprises a complex cascade of reactions that balances effector and regulatory functions.1 While the effector’s arm includes cellular and molecular components responsible for preventing cellular infections and…
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INTRODUCTIONHzailey-Hailey disease (HHD), or benign familial pemphigus, is an uncommon blistering disorder that presents as recurrent vesicles and erosions. These lesions often appear in the third to fourth decade of…
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INTRODUCTIONLocal anesthesia is used in over one-million cutaneous surgeries per year, allowing providers to successfully perform many outpatient and office-setting surgeries.1 However, administration of local anesthesia has drawbacks, including the…
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INTRODUCTIONRecurrent aphthous stomatitis (RAS) is the most common oral lesion; it has unknown etiology and is characterized by periodic oval, shallow, painful ulcers, gray or yellowish in color, which are…
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