INTRODUCTIONExtramammary Paget Disease (EMPD) is a rare intraepithelial malignancy of pluripotent keratinocyte stem cells that presents on apocrine-rich skin of the perineum, vulva, and less commonly, axilla.1 EMPD clinically presents…
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INTRODUCTIONPsoriasis is a chronic inflammatory disease that affects more than 7.5 million people in the United States.1 Although psoriasis is most prevalent in whites (3.2%), African Americans often exhibit more…
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INTRODUCTIONBaricitinib is a reversible Janus kinase (JAK) 1 and 2 inhibitor approved for use in the European Union and the United States for various dermatological conditions. In the US, current…
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INTRODUCTIONPlaque psoriasis is a chronic, inflammatory skin disorder spanning a patient's lifetime and hence requires long-term management.1 Psoriasis is a multisystem disease that remarkably impacts patients' physical health and is…
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INTRODUCTIONPsoriasis is a chronic, immune-mediated, multisystem, inflammatory dermatological condition that is persistent and relapsing.1 It affects 3.2% of the American adult population and an estimated 125 million people worldwide. The…
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INTRODUCTIONTopical corticosteroids (TCS) continue to be a mainstay of primary and/or adjunctive therapy for all severities of psoriasis. Corticosteroid-containing topical medications include both monotherapy and combination formulations with vitamin D…
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INTRODUCTIONPsoriasis (PsO) is a chronic, inflammatory skin disease characterized by cutaneous features, extracutaneous comorbidities, and an unpredictable course.1,2 PsO is the second most common chronic pediatric skin disorder after atopic…
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INTRODUCTIONPsoriasis vulgaris is a chronic, immune-mediated skin disease originating from a combination of environmental and genetic factors. Approximately 80% of psoriasis patients exhibit mild-to-moderate disease, for which topical therapies remain…
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INTRODUCTIONVariations in the epidemiology, clinical presentation, disease course, and impact on quality of life have been reported in SOC populations.1 Epidemiologic studies focused on atopic dermatitis (AD) suggest a higher…
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INTRODUCTIONAlopecia areata (AA) is an autoimmune hair loss disorder arising due to loss of hair follicle immune privilege.1 Increased antigen presentation at the bulb of the hair follicle leads to…
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INTRODUCTIONCurrent Treatments and Unmet Needs in Psoriasis Psoriasis is a chronic, immune-mediated skin disease that affects approximately 8 million adults in the Unite States and 2% to 3% of people…
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INTRODUCTIONHidradenitis suppurativa (HS) is a chronic, oftentimes debilitating inflammatory skin condition characterized by abscesses, inflammatory nodules, sinus tracts, and scarring.1 Existing data suggest multifactorial etiology with genetic, hormonal, and immune…
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