Dear Editor, Interleukin 36 (IL-36) inhibitors block the interaction of IL-36 and its receptor, attenuating the downstream inflammatory signaling cascade.1 Given the therapeutic potential for IL-36 inhibitors in treating dermatological…
Read More
INTRODUCTIONCutaneous collagenous vasculopathy (CCV) is a rare, idiopathic, cutaneous microangiopathy first reported in the early 2000s.1 It presents as diffuse telangiectasias, initially appearing on the lower extremities, and sometimes spreading…
Read More
INTRODUCTIONDermatology has benefited from multiple technological advancements, including total body photography (TBP)1,2 and teledermatology.3 These technological leaps were made possible with the introduction of digital photography, especially with the advent…
Read More
INTRODUCTIONFrom 2005 to 2020, the percentage of American adults using social media skyrocketed.1 For many, social media is a means of "researching" everyday needs, including healthcare.1,2 While mass dissemination of…
Read More
INTRODUCTIONNaltrexone is an FDA-approved opioid receptor antagonist for the treatment of opioid and alcohol use disorder at standard doses of 50 to 100 milligrams (mg) daily. Low-dose naltrexone (LDN), 1…
Read More
INTRODUCTIONScarring alopecia, also known as cicatricial alopecia, is a hair loss due to the destruction of epithelial stem cells at the hair follicle bulge mediated by inflammation, infection, or other…
Read More
INTRODUCTIONDue to the high risk of recurrence, excision with clear histological margins is the preferred treatment modality for lentigo maligna (LM) and lentigo maligna melanoma (LMM).1 Conventional wide-local excision (WLE)…
Read More
INTRODUCTIONHidradenitis suppurativa (HS) is a chronic condition that presents with inflammatory lesions which commonly present at sites bearing apocrine glands. HS is a multifactorial disease, and factors such as genetics,…
Read More
INTRODUCTIONExposure to solar radiation (SR) is associated with a range of adverse effects on the skin, including photocarcinogenesis, sunburn, photoaging, and pigmentation. While the primary focus of SR-induced pathologies has…
Read More
INTRODUCTIONAcne affects approximately 50 million people in the United States.1 Therapies include retinoids, antibiotics, hormones, lights, lasers, and various combinations of these modalities.2 Topical and/or oral medications are associated with…
Read More
INTRODUCTIONDespite numerous public warnings about protecting the skin against sun's UV exposure and extensive research into topical protective formulations, the incidence of melanoma and non-melanoma skin cancers continues to rise.1…
Read More
INTRODUCTIONThe glucagon-like peptide-1 receptor agonists (GLP1RAs) are a widely popularized drug class due to their notable success in promoting weight loss. The GLP1RAs, dulaglutide, exenatide, semaglutide, liraglutide, tirzepatide, and lixisenatide…
Read More
