CASE REPORT A 77-year-old woman with a diagnosis of breast carcinoma underwent a right mastectomy followed by radiotherapy. Thereafter, she was started on tamoxifen 20 mg a day by the…

INTRODUCTION Fixed drug eruption, first described by Bourns in the late nineteenth century, is classically characterized by solitary or multiple, round to oval, sharply demarcated, erythematous patches that occur on…

New Drug Applications For Vemurafenib In Advanced Skin Cancer Genentech has announced that it has submitted a New Drug Application to the FDA for vemurafenib (RG7204, PLX4032), a potential treatment…

A 37-year-old white woman on over 10 years of immunosuppressive therapy for two successive renal transplants was seen in our dermatology clinic for a tender lesion on her left eyebrow…

INTRODUCTION This edition of Resident Spotlight features Michael McLeod's winning poster,“Predictive Factors for Severity of Scar Formation After Skin Cancer Surgeries ” from the Orlando Dermatology Aesthetic & Clinical Conference…

Merkel Cell Carcinoma: Banal-Appearing, Aggressive Actor Abstract Merkel cell carcinoma is a rare but often deadly cutaneous malignancy. It carries a 40 percent five-year mortality rate, in contrast to 15…

INTRODUCTION Psoriasis affects nearly 7.5 million Americans and 125 million people worldwide.1 It exists in two phases: the acute, flaring state and the chronic, indolent state. We designate the acute…

BACKGROUNDDermatofibrosarcoma protuberans (DFSP) is an uncommon dermal and subcutaneous neoplasm with a predilection for the trunk of young to middle-aged adults. The tumor presents clinically as solitary or multiple skin-colored,…

INTRODUCTION Psoriasis is a chronic, immune-mediated, inflammatory skin disease that affects approximately 3% of the population in the United States (U.S.),1 or 6.4 million people.2 Recently, more emphasis has been…

INTRODUCTION Pruritus is a common aspect of many conditions including urticaria, psoriasis, atopic dermatitis, renal failure and cholestasis. It is generally recognized that pruritus has a profound effect on quality-of-life…

INTRODUCTIONPsoriasis is a chronic, immune-mediated, inflammatory condition that occurs worldwide; frequency varies greatly among different racial and ethnic groups.1,2 The prevalence of psoriasis has been estimated at 1.3 percent in…

INTRODUCTION Psoriasis is caused by the interplay of various cellular processes in the skin, including keratinocyte hyperplasia, vascular proliferation and lymphocyte infiltration.1 Its multi-factorial etiology calls for many therapeutic agents…