INTRODUCTION Sorafenib (Nexavar), a multikinase inhibitor (MKI), is available for the treatment of metastatic or unresectable hepatocellular carcinoma (HCC), advanced renal cell carcinoma, and other solid tumors. Sorafenib inhibits cell…

ACNEEpiduo Pediatric Acne Study Sponsored by Galderma. The purpose of this study is to evaluate the safety and efficacy of Epiduo (adapalene and benzoyl peroxide) Gel 0.1%/2.5% administered once daily…

Second Cancers After Melanoma: For Which Cancers Are Melanoma Patients at Higher Risk? Which Malignancies Predispose to Melanoma? Cutaneous melanoma is often diagnosed in young and middleaged individuals. After a…

Herpes Zoster Vaccine Reduces Zoster Risk The results of a new community-based study published in the January 12 issue of the Journal of the American Medical Association show that vaccination…

The Eastern Virginia Medical School was founded as a private community-based medical school in 1973 by local physicians who saw a need for medical education in the underserved coastal Virginia…

INTRODUCTION While highly effective in reducing rhytides, photoaging and acne scarring, standard ablative laser resurfacing was associated with significant side effects and complications.1 In an effort to improve patient safety,…

ACKNOWLEDGEMENTS The authors would like to thank John Foss, BS for his assistance with the computer graphics. DISCLOSURES The authors have no relevant conflicts of interest to disclose.

INTRODUCTIONPsoriasis is a chronic immunologically driven inflammatory disease characterized by infiltration of the skin with activated T cells and by abnormal keratinocyte proliferation and differentiation, resulting in marked inflammation and…

INTRODUCTIONActinic keratosis (AK), a highly prevalent dermatologic condition resulting from long-term sun exposure,1,2 most commonly occurs in older individuals and those with fair skin.1-3 AKs are typically present as red,…

INTRODUCTIONHidradenitis suppurativa (HS) is a chronic, often recalcitrant condition that primarily affects apocrine glandbearing skin in the axillae, groin and buttocks. Histopathologic studies show that follicular occlusion rather than inflamed…

INTRODUCTIONThe majority of changes we associate with aging are the results of chronic photodamage and include five main features: fine lines and wrinkles, enlarged pores, sagging skin, telangiectasias and dyschromia…

INTRODUCTIONTumour necrosis factor-α (TNFα) inhibitors have changed the way we treat patients that suffer with moderate to severe chronic plaque psoriasis (PsO). Three TNF inhibitors have been approved by the…