INTRODUCTIONAcne vulgaris is a chronic inflammatory disease that affects pilosebaceous units on the face and trunk requiring longitudinal patient management.1,2 It has a multifactorial pathophysiology that involves an altered sebaceous…
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INTRODUCTIONA member of the tyrosine-protein kinase Tec (TEC) family of tyrosine kinases, Bruton tyrosine kinase (BTK) is a cytoplasmic, nonreceptor kinase essential to myriad immunological pathways.1 Activity of BTK most…
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INTRODUCTION Challenging body areas include the scalp, face, palmoplantar surfaces (ie, palms and soles), nails, intertriginous areas, and genitalia. Psoriasis involving challenging body areas is associated with a higher degree…
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INTRODUCTIONPlaque psoriasis is a chronic, relapsing systemic illness that has a significant effect on quality of life.1-3 New biologic therapies targeting tumor necrosis factor (TNF), interleukin (IL)-12/23, IL-17, and IL-23…
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INTRODUCTIONPsoriasis is a chronic inflammatory disorder primarily affecting the skin and joints. It affects different racial/ethnic groups worldwide with varying prevalence. Although psoriasis has historically been considered to predominately affect…
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INTRODUCTIONNarrow band-ultraviolet B (NB-UVB) light therapy has been shown to be one of the safest, least expensive, and most effective treatments for psoriasis.1 Traditional clinic-based phototherapy is time-consuming, expensive, and…
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INTRODUCTIONMelanoma accounts for only 1% of all skin cancers but is responsible for most skin cancer-related deaths.1 Acral and mucosal melanoma (AMM) accounts for only 4% of all new melanomas…
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INTRODUCTIONAtopic dermatitis (AD), commonly known as eczema, is a common chronic inflammatory skin condition, characterized by dry, itchy skin, making individuals more susceptible to skin infections and other complications.1 This…
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INTRODUCTIONThe combined use of topical calcipotriol/betamethasone dipropionate (Cal/BDP) is commonly used and demonstrated to be effective for the management of psoriasis. Used in combination, topical calcipotriol, and betamethasone dipropionate confer…
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INTRODUCTIONPsoriasis is a chronic inflammatory skin disease that affects nearly 8 million adults in the United States (US).1 The disease is characterized by sharply demarcated, scaly, erythematous plaques that can…
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INTRODUCTIONSome psoriatic disease topical treatments, such as coal tar and salicylic acid, have stood the test of time, being used consistently over the past century.1 However, the landscape of systemic…
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INTRODUCTIONPsoriasis is a chronic inflammatory disorder affecting up to 2% to 4% of the general population worldwide.1 The treatment of moderate-to-severe psoriasis includes systemic disease-modifying antirheumatic drugs (DMARDs), such as…
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