INTRODUCTIONAcne is a chronic inflammatory disease of the pilosebaceous units. It is characterized by seborrhea, the formation of comedones, erythematous papules and pustules, less frequently by nodules and pseudocysts, and…

INTRODUCTION Cutaneous tolerability is a significant concern for any acne therapy and has played an important role in the development of topical retinoids. The hydroalcoholic formulation of tretinoin, the first…