FULL SUPPLEMENT: Status Update: Isotretinoin

May 2021 | Volume 20 | Issue 5 | Department | 1s | Copyright © May 2021


Published online April 28, 2021

Abstract
In this supplement:

Why Absorica LD?
For close to four decades, isotretinoin has been a mainstay treatment for severe nodular acne. It was the first and still remains the only oral therapy shown to address all four pathogenic factors of acne including hyper-keratinization, sebum production, Cutibacterium acnes proliferation, and inflammation.

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Advances in Oral Isotretinoin Therapy
Before isotretinoin, no other acne therapy targeted all four pathogenesis factors of acne (including hyper-keratinization, sebum production, Cutibacterium acnes proliferation, and inflammation).1,2 Rather, other non-isotretinoin treatments for acne are often used in combination to address multiple aspects of acne pathogenesis at once.3 Isotretinoin, available in the US for almost four decades, is an oral retinoid recommended as a first-line treatment option for treating severe nodular acne.

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